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New Possibilities for Biospecific Chromatography

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Abstract

Polyacrylamide hydrogels covalently modified with duck eggwhite ovomucoid were synthesized by radical copolymerization. These hydrogels can protect insulin (physically immobilized therein) against the action of proteolytic enzymes. Biospecific interaction of the polysaccharide component of the ovomucoid with lectins targets the hydrogel particles to the wall of the small intestine.

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Authors and Affiliations

  1. Russian Academy of Sciences, Topchiev Institute of Petrochemical Synthesis, Leninskii prospekt 29, Moscow, 117912, Russia

    I. L. Valuev, L. I. Valuev & N. A. Platé

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  1. I. L. Valuev
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  2. L. I. Valuev
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  3. N. A. Platé
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Valuev, I.L., Valuev, L.I. & Platé, N.A. New Possibilities for Biospecific Chromatography. Applied Biochemistry and Microbiology 39, 422–425 (2003). https://doi.org/10.1023/A:1024584905184

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