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3-Cyanopyridine-2(1H)-thiones and 3-cyano-2-(methylthio)pyridines in the synthesis of substituted 3-(aminomethyl)pyridines

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Abstract

The reactions of substituted 3-cyanopyridine-2(1H)-thiones and 3-cyano-2-(methylthio)pyridines with lithium aluminum hydride in anhydrous diethyl ether afforded the corresponding 3-aminomethyl derivatives, which were used in the synthesis of the corresponding amides.

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Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

    A. A. Zubarev, V. K. Zavyalova & V. P. Litvinov

Authors
  1. A. A. Zubarev
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  2. V. K. Zavyalova
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  3. V. P. Litvinov
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Zubarev, A.A., Zavyalova, V.K. & Litvinov, V.P. 3-Cyanopyridine-2(1H)-thiones and 3-cyano-2-(methylthio)pyridines in the synthesis of substituted 3-(aminomethyl)pyridines. Russian Chemical Bulletin 52, 978–983 (2003). https://doi.org/10.1023/A:1024472914598

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