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Structural and Functional Characteristics of Lymphocytes in Chronic Carriers of Tick-Borne Encephalitis Virus

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Abstract

Study of the surface phenotype, structure of plasma membrane, and activity of DNA repair system in peripheral blood lymphocytes from patients with different clinical forms of tick-borne encephalitis associated with long persistence of the virus revealed a pronounced imbalance between lymphocyte subpopulations, increased microviscosity of the plasma membrane lipid phase, and decreased activity of the DNA repair system in lymphocytes.

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Authors and Affiliations

  1. Siberian State Medical University, Russia

    N. V. Ryazantseva, O. B. Zhukova, V. V. Novitskii, N. P. Pirogova, A. V. Lepekhin, N. V. Tokareva, O. V. Mikhailova, N. N. Plotnikova & N. V. Sevost'yanova

  2. Institute of Pharmacology, Tomsk Research Center, Siberian Branch of Russian Academy of Medical Sciences, Russia

    N. V. Ryazantseva, O. B. Zhukova, V. V. Novitskii, N. P. Pirogova, A. V. Lepekhin, N. V. Tokareva, O. V. Mikhailova, N. N. Plotnikova & N. V. Sevost'yanova

  3. Institute of Oncology, Tomsk Research Center, Siberian Branch of Russian Academy of Medical Sciences, Russia

    N. V. Ryazantseva, O. B. Zhukova, V. V. Novitskii, N. P. Pirogova, A. V. Lepekhin, N. V. Tokareva, O. V. Mikhailova, N. N. Plotnikova & N. V. Sevost'yanova

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  1. N. V. Ryazantseva
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  2. O. B. Zhukova
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  3. V. V. Novitskii
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  4. N. P. Pirogova
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  5. A. V. Lepekhin
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  6. N. V. Tokareva
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  7. O. V. Mikhailova
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  8. N. N. Plotnikova
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  9. N. V. Sevost'yanova
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Ryazantseva, N.V., Zhukova, O.B., Novitskii, V.V. et al. Structural and Functional Characteristics of Lymphocytes in Chronic Carriers of Tick-Borne Encephalitis Virus. Bulletin of Experimental Biology and Medicine 134, 471–473 (2002). https://doi.org/10.1023/A:1022698532379

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  • DOI: https://doi.org/10.1023/A:1022698532379

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