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Synthesis and Biological Properties of Isoquinolines Spirofused with Carbocycles and Heterocycles at Position 4. (Review)

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Published data on the synthesis and biological properties of isoquinolines spirofused with carbocycles and heterocycles at position 4 are reviewed. The methods of synthesis are classified according to the formation of the isoquinoline fragment or the carbocycle or heterocycle fused with it during the construction of the spirocyclic system. Data on the biological activity are arranged according to the types of action exhibited by the compounds.

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  1. Taras Shevchenko Kiev National University, Kiev, Ukraine

    V. M. Kisel', E. O. Kostyrko & V. A. Kovtunenko

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Kisel', V.M., Kostyrko, E.O. & Kovtunenko, V.A. Synthesis and Biological Properties of Isoquinolines Spirofused with Carbocycles and Heterocycles at Position 4. (Review). Chemistry of Heterocyclic Compounds 38, 1295–1318 (2002). https://doi.org/10.1023/A:1022166023234

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