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Modified Coumarins. 5. Amino-Acid Derivatives of 3-Hydroxy-7,8,9,10-tetrahydrobenzo[c]Chromen-6-one

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Abstract

Peptide-chemistry methods (symmetric anhydrides and activated esters) and the Mannich reaction were used to prepare various conjugates of amino acids with 7,8,9,10-tetrahydrobenzo[c]chromen-6-one in which the amino acids are bound to the coumarin by the C- or N-terminus.

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Authors and Affiliations

  1. Institute of Bioorganic and Petroleum Chemistry, National Academy of Sciences, the Ukraine, 02094, the Ukraine, Kiev, ul. Murmanskaya, 1

    M. M. Garazd

  2. Taras Shevchenko Kiev National University, 01033, the Ukraine, Kiev, ul. Vladimirskaya, 64

    Ya. L. Garazd, S. V. Shilin & V. P. Khilya

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  1. M. M. Garazd
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  2. Ya. L. Garazd
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  3. S. V. Shilin
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  4. V. P. Khilya
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Garazd, M.M., Garazd, Y.L., Shilin, S.V. et al. Modified Coumarins. 5. Amino-Acid Derivatives of 3-Hydroxy-7,8,9,10-tetrahydrobenzo[c]Chromen-6-one. Chemistry of Natural Compounds 38, 416–423 (2002). https://doi.org/10.1023/A:1022151407961

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