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Relationship between Alcohol Motivation and Ethanol Sensitivity and Blood and Brain Catecholamine Content in the Progeny of Rats Preferring and Nonpreferring Alcohol

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Abstract

A system of neurochemical signs indicating predisposition to high ethanol consumption is formed in the third generation descendants of ethanol-preferring male rats. Risk-group males are detected (with 95% probability) by the content of dopamine and norepinephrine and their ratio in the brain. Alcohol motivation depends on blood epinephrine content reflecting individual sensitivity to stress.

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Authors and Affiliations

  1. Institute of Drug Abuse, Ministry of Health of Russian Federation, Moscow

    I. P. Anokhina, A. V. Stanishevskaya, O. F. L'vova, A. G. Veretinskaya & N. A. Khristolyubova

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  1. I. P. Anokhina
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  2. A. V. Stanishevskaya
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  3. O. F. L'vova
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  4. A. G. Veretinskaya
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  5. N. A. Khristolyubova
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Anokhina, I.P., Stanishevskaya, A.V., L'vova, O.F. et al. Relationship between Alcohol Motivation and Ethanol Sensitivity and Blood and Brain Catecholamine Content in the Progeny of Rats Preferring and Nonpreferring Alcohol. Bulletin of Experimental Biology and Medicine 134, 351–354 (2002). https://doi.org/10.1023/A:1021952113490

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  • DOI: https://doi.org/10.1023/A:1021952113490

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