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Effect of Maksar on Antioxidant System in Rats with Type IIa Alimentary Hyperlipoproteinemia

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Abstract

The development of type IIa alimentary hyperlipoproteinemia in rats was accompanied by changes in activity of glutathione-dependent enzymes, exhaustion of the reserves of antioxidant vitamins in the liver and blood, and intensification of lipid peroxidation. The hepatoprotective preparation Maksar obtained from far-eastern plants Maachia amurensis and containing natural biological antioxidants normalized blood lipid composition, corrected liver lipidosis, and improved the antioxidant defense system.

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Authors and Affiliations

  1. Vladivostok Branch, Far-Eastern Research Center for Physiology and Pathology of Respiration, Siberian Division of the Russian Academy of Medical Sciences, Institute of Medical Climatology and Rehabilitative Therapy; Pacific Institute of Bioorganic Chemistry, Far-Eastern Division of the Russian Academy of Sciences, Vladivostok, Russia

    V. I. Yan'kova, T. A. Gvozdenko, I. L. Ivanova, S. A. Fedoreev & N. I. Kulesh

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  1. V. I. Yan'kova
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  2. T. A. Gvozdenko
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  3. I. L. Ivanova
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  4. S. A. Fedoreev
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  5. N. I. Kulesh
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Yan'kova, V.I., Gvozdenko, T.A., Ivanova, I.L. et al. Effect of Maksar on Antioxidant System in Rats with Type IIa Alimentary Hyperlipoproteinemia. Bulletin of Experimental Biology and Medicine 134, 230–232 (2002). https://doi.org/10.1023/A:1021439030694

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  • DOI: https://doi.org/10.1023/A:1021439030694

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