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Synthesis of 3-carbamoyl-1,2,4-oxadiazoles

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Abstract

A convenient method for the synthesis of 3-carbamoyl-1,2,4-oxadiazoles from carbamoylamidoximes and chlorides or anhydrides of haloacetic acids was developed. The reactions of 3-carbamoyl-5-trichloromethyl-1,2,4-oxadiazoles with amines and N,N-dimethylhydrazine were studied.

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Authors and Affiliations

  1. Russian Academy of Sciences, N. D. Zelinsky Institute of Organic Chemistry, 47 Leninsky prosp., 119991, Moscow, Russian Federation

    V. N. Yarovenko, S. A. Kosarev, I. V. Zavarzin & M. M. Krayushkin

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  1. V. N. Yarovenko
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  2. S. A. Kosarev
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  3. I. V. Zavarzin
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  4. M. M. Krayushkin
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Yarovenko, V.N., Kosarev, S.A., Zavarzin, I.V. et al. Synthesis of 3-carbamoyl-1,2,4-oxadiazoles. Russian Chemical Bulletin 51, 1857–1861 (2002). https://doi.org/10.1023/A:1021348401329

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  • DOI: https://doi.org/10.1023/A:1021348401329

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