Abstract
A general and convenient method for the synthesis of 11-aryl-1-oxo-2,3,4,5,10b,11-hexahydro-1H-indolo[2,3-b]quinoline-10b-carbonitriles was elaborated. The method is based on the novel stereoselective rearrangement of fused N-arylamino-substituted 1,4-dihydropyridines. The structures of the synthesized compounds were studied using 1H NMR spectroscopy and X-ray diffraction analysis.
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Lichitsky, B.V., Kozhinov, D.V., Nesterov, V.N. et al. Reactions of cyclic enehydrazino ketones with arylidenemalononitriles. Synthesis of 11-aryl-1-oxo-2,3,4,5,10b,11-hexahydro-1H-indolo[2,3-b]quinoline-10b-carbonitriles. Russian Chemical Bulletin 51, 1862–1868 (2002). https://doi.org/10.1023/A:1021300518167
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DOI: https://doi.org/10.1023/A:1021300518167