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Membrane and Intracellular Components in Adaptation to Physical Factors of Alpine Regions

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This study considers key membrane and intracellular messenger effector mechanisms in adaptation to physical factors of alpine regions (3200 m above sea level, 10°C, 60 days). The detergent potential of free radicals and lysophospholipids promotes conditions required for phospholipid and fatty acid recomposition in membranes that is adequate to changes in the environment. The content of polyphosphoinositides increases in the membrane fraction of total inositol phospholipids during the second stage of activity of the hormonal system in alpine regions, which results in new correlations between the hormonal and messenger systems.

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Authors and Affiliations

  1. Institute of High-Altitude Physiology and Experimental Pathology, Academy of Sciences of Kyrgyzstan, Bishkek, Kyrgyzstan

    A. A. Vishnevskii, V. M. Yakovlev, Z. I. Khabibullova & B. M. Mukambetova

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  1. A. A. Vishnevskii
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  2. V. M. Yakovlev
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  3. Z. I. Khabibullova
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  4. B. M. Mukambetova
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Vishnevskii, A.A., Yakovlev, V.M., Khabibullova, Z.I. et al. Membrane and Intracellular Components in Adaptation to Physical Factors of Alpine Regions. Human Physiology 28, 672–675 (2002). https://doi.org/10.1023/A:1021144121143

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