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Synthesis of substituted bis(3,3-dialkyl-3,4-dihydro-1-isoquinolyl)methanes

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Abstract

Symmetrical and non-symmetrical substituted bis(3,4-dihydro-1-isoquinolyl)methanes were synthesized by fusion of substituted 1-methylthio-3,4-dihydroisoquinolines with 1-methyl-3,4-dihydroisoquinolines and by the Ritter reaction of 1,1-dialkyl-2-arylethanols with 1-cyanomethylidene-1,2,3,4-tetrahydroisoquinoline or malononitrile.

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Glushkov, V.A., Karmanov, V.I. & Shklyaev, Y.V. Synthesis of substituted bis(3,3-dialkyl-3,4-dihydro-1-isoquinolyl)methanes. Russian Chemical Bulletin 51, 1303–1307 (2002). https://doi.org/10.1023/A:1020917000475

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  • DOI: https://doi.org/10.1023/A:1020917000475

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