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Synthesis and Tuberculostatic Activity of Methyl 3-Isonicotinoyldithiocarbazate and S,S'-Dimethyl Dithiocarbonate Isonicotinoylhydrazone, and Their Reactions with Amines and Hydrazines

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Abstract

Methyl 3-isonicotinoyldithiocarbazates and S,S'-dimethyl dithiocarbonate isonicotinoylhydrazone were prepared. Their reactions with primary and secondary amines, diamines, and hydrazines were studied. The newly obtained derivatives did not show tuberculostatic activity in vitro.

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Authors and Affiliations

  1. Department of Organic Chemistry, Medical University of Gdansk, 80-416, Gdansk, Poland

    H. Foks & J. Mieczkowska

  2. Department of Microbiology, Institute of Tuberculosis Pulmonary Diseases, 01-138, Warszawa, Poland

    M. Janowiec, Z. Zwolska & Z. Andrzejczyk

Authors
  1. H. Foks
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  2. J. Mieczkowska
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  3. M. Janowiec
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  4. Z. Zwolska
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  5. Z. Andrzejczyk
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Foks, H., Mieczkowska, J., Janowiec, M. et al. Synthesis and Tuberculostatic Activity of Methyl 3-Isonicotinoyldithiocarbazate and S,S'-Dimethyl Dithiocarbonate Isonicotinoylhydrazone, and Their Reactions with Amines and Hydrazines. Chemistry of Heterocyclic Compounds 38, 810–816 (2002). https://doi.org/10.1023/A:1020681604052

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  • DOI: https://doi.org/10.1023/A:1020681604052

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