Abstract
The authors report on a rare pediatric case of adrenal extramedullary hematopoiesis in a patient with beta-thalassemia disease. The lesion was clinically discovered as incidentaloma of the right adrenal gland and treated by surgery. Adrenal extramedullary hematopoiesis may clinically be detected as incidentaloma. Adrenal incidentalomas presenting with hematologic disorders, such as agnogenic myeloid aplasia and beta-thalassemia, need careful imaging as well as adrenal hormonal investigation in order to exclude malignancy and sublinical hypersecretory syndromes. Ultrasound or CT-FNA of the lesion are effective in finding out the disease.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Redlin L, Francis RS, Orlando MM. Renal abnormalitiesin agnogenic myeloid metaplasia. Radiology 1976; 121: 605–608.
Moskovitz B, Malberger E, Brenner B et al. Renal extramedullary hematopoiesis simulating hypernephroma. EurUrol 1991; 19: 343–345.
Sharma AK. Tumefactive extramedullary hematopoiesis of the kidney in a patient with idiopathic thrombocytopenic purpura. AJR 1996; 167: 795.
Saisorn I, Leewansangtong S, Suckpanichant S et al. Intrarenal extramedullary hematopoiesis as a renal mass in a patient with thalassemia. J Urol 2001; 165: 507–508.
Wyatt JP, Sommers SC. Chronic marrow failure, myelosclerosis and extramedullary hematopoiesis. Blood 1950; 5: 329–347.
Pitcock JA, Reinhard EH, Justus BW, Mendelsohn RS. A clinical and pathological study of seventy cases of myelofibrosis. Ann Intern Med 1962; 57: 73–84.
Ward HP, Block MH. The natural history of agnogenic myeloid metaplasia (AMM) and a critical evaluation of its relationship with the myeloproliferative syndrome. Medicine (Baltimore 1971); 50: 357–420.
King BF, Kopecky KK, Baker MK, Clark SA. Extramedullary hematopoiesis in the adrenal glands: CT characteristics. Journal of Computer Assisted Tomography 1987; 11: 342–343.
Wat NMS, Tse KKM, Chan FL, Lam KSL. Adrenal extramedullary hematopoiesis: diagnosis by a non-invasive method. British Journal of Haematology 1998; 100: 725–727.
Porcaro AB, Novella G, Ficarra V et al. Adrenal incidentalomas: surgical treatment in 28 patients and update of the literature International Urology and Nephrology 2001; 32: 295–302.
Mahhoran A, Pitney WR. Chemotherapy resolves symptoms and reverses marrow fibrosis in myelofibrosis. Scand J Haematol 1984; 33: 453–457.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Porcaro, A.B., Novella, G., Antoniolli, S.Z. et al. Adrenal extramedullary hematopoiesis: Report on a pediatric case and update of the literature. Int Urol Nephrol 33, 601–603 (2001). https://doi.org/10.1023/A:1020578501167
Issue Date:
DOI: https://doi.org/10.1023/A:1020578501167