Skip to main content
SpringerLink
Log in

Extramedullary Hematopoiesis in Adrenal Incidentaloma: Case Report of an Atypical Histopathological Finding

  • Case Report
  • Published:
Indian Journal of Surgery Aims and scope Submit manuscript

Abstract

Adrenal gland extramedullary hematopoiesis is extremely rare, and when present, imaging studies may mimic an incidentaloma suspicious of malignancy. We present a 55-year-old woman without a history of hematologic disorder or neoplasms. There was an incidental finding of a 3.2 × 2.4-cm heterogenous adrenal mass and enhanced by contrast abdominal CT scan. Suspicious of malignancy was established, and laparoscopic left adrenalectomy was performed. Histopathological examination and immunohistochemical staining exhibited myeloid and erythroid precursors, as well as megakaryocyte confirming the diagnosis of extramedullary hematopoiesis in the adrenal gland.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Fan F, Lavu S, Hanson CA et al (2018) Extramedullary hematopoiesis in the absence of myeloproliferative neoplasms: Mayo Clinic case series of 309 patients. Blood Cancer J 8(12):119

    Article  CAS  Google Scholar 

  2. Salemme M, Rodella R, Fisogni S et al (2011) Nodular extramedullary hematopoiesis involving the adrenal gland. An uncommon cause of adrenal “incidentaloma”. Pathologica 103:46–49

    CAS  PubMed  Google Scholar 

  3. Sargar KM, Khanna G, Hulett BR (2017) Imaging of nonmalignant adrenal lesions in children. Radiographics 37(6):1648–1664

    Article  Google Scholar 

  4. Kolev NH, Genov PP, Dunev VR et al (2020) A rare case of extramedullary hematopoiesis in adrenal mass. Urology Case Reports 30. https://doi.org/10.1016/j.eucr.2020.101120

  5. Banerji JS, Kumar RM, Devasia A (2013) Extramedullary hematopoiesis in the adrenal: case report and review of literature. Can Urol Assoc J 7:E436–E438

    Article  Google Scholar 

  6. Sekar S, Burad D, Abraham A et al (2015) Adrenal incidentaloma caused by extramedullary haematopoiesis: conservative management is optimal. BMJ Case Rep. https://doi.org/10.1136/bcr-2015-211014

  7. King BF, Kopecky KK, Baker MK et al (1987) Extramedullary hematopoiesis in the adrenal glands: CT characteristics. J Comput Assist Tomogr 11:342–343

    Article  CAS  Google Scholar 

  8. Wat NM, Tse KK, Chan FL et al (1998) Adrenal extramedullary haemopoiesis: diagnosis by a non-invasive method. Br J Haematol 100:725–727

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Endocrine and Advanced Laparoscopic Surgery Service, Deparment of Surgery, North Central Hospital PEMEX, Calle Campo Matillas 52, San Antonio, Azcapotzalco, 02760, Mexico City, Mexico

    Jorge Montalvo-Hernández

  2. Clinical Endocrinology, North Central Hospital PEMEX, Calle Campo Matillas 52, San Antonio, Azcapotzalco, 02760, Mexico City, Mexico

    José Alfredo Álvarez-López

  3. Deparment of Anatomical Pathology, North Central Hospital PEMEX, Calle Campo Matillas 52, San Antonio, Azcapotzalco, 02760, Mexico City, Mexico

    Rafael Silva

  4. Endocrine and Advanced Laparoscopic Surgery Service, Deparment of Surgery, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Vasco de Quiróga No. 15 Colonia Sección XVI, Tlalpan, 14080, Mexico City, Mexico

    Rafael Humberto Pérez-Soto

Authors
  1. Jorge Montalvo-Hernández
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. José Alfredo Álvarez-López
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Rafael Silva
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Rafael Humberto Pérez-Soto
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jorge Montalvo-Hernández.

Ethics declarations

Conflict of Interest

The authors declare that they have no conflict of interest.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Montalvo-Hernández, J., Álvarez-López, J.A., Silva, R. et al. Extramedullary Hematopoiesis in Adrenal Incidentaloma: Case Report of an Atypical Histopathological Finding. Indian J Surg 83, 1286–1289 (2021). https://doi.org/10.1007/s12262-020-02661-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12262-020-02661-6

Keywords

Search

Navigation