Skip to main content
Log in

Immunobiochemical Characteristics of IgG Antibodies in Myasthenia

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The abzyme activity of mAb35 and pQ1-209 was compared with that of normal rabbit IgG and serum IgG from patients with various forms of myasthenia. It was found that mAb35 and pQ1-209 and IgG from patients with myasthenia possess catalytic activity. IgG from myasthenia patients with thymomas possess creatine phosphokinase activity, which 2- fold surpassed the control.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

REFERENCES

  1. I. I. Generalov and D. K. Novikov, Uspekhi Sovrem. Biol., 118,No. 2, 178–193 (1998).

    Google Scholar 

  2. I. I. Generalov and E. V. Sidorskaya, Immunologiya, No. 3, 54–56 (1998).

  3. I. I. Generalov and D. K. Novikov, Immunopatol., Allergol., Infektol., No. 1, 99–125 (1999).

  4. M. I. Kuzin and B. M. Hecht, Myasthenia [in Russian], Moscow (1996), pp. 24–29.

  5. E. V. Sidorkskaya, I. I. Generalov, and A. N. Okorokov, Immunopatol., Allergol., Infektol., No. 1, 57–61 (2000).

  6. Basic Protein and Peptide Protocols, Ed. J. M. Walker, Totowa (1994), p. 490.

  7. D. Franciotta, M. Gianvito, E. Brambilla, et al., Clin. Chem., 45,No. 3, 400–405 (1999).

    Google Scholar 

  8. C. Lena and J.-P. Changeux, J. Physiol. (Paris), 92, 63–74 (1998).

    Google Scholar 

  9. K. Oda, Ann. N. Y. Acad. Sci., 681, 238–255 (1993).

    Google Scholar 

  10. Th. Tsouloufis, A. Mamalaki, M. Remoundos, and S. J. Tzartos, Int. Immunol., 12,No. 9, 1255–1265 (2000).

    Google Scholar 

  11. A. Vincent, Brain Behav. Immun., 2, 346–351 (1988).

    Google Scholar 

  12. A. Vincent and J. Newsom-Davis, J. Neurosurg. Psychiatry, 48, 1246–1252 (1985).

    Google Scholar 

  13. C. W. Zimmermann and F. Ebben, Clin. Invest., 71, 445–451 (1993).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lantsova, V.B.E.K. Immunobiochemical Characteristics of IgG Antibodies in Myasthenia. Bulletin of Experimental Biology and Medicine 133, 588–590 (2002). https://doi.org/10.1023/A:1020294111513

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1020294111513

Navigation