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Production of artemisinin by hairy root cultures of Artemisia annua L

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Abstract

Using a combination of sucrose (70 g/L), nitrate (30 mM), inorganic phosphate (1.5 mM), gibberellic acid (5 mg/L) and the ratio of N (NH ) to N - (NO ) (1:5), artemisinin production was increased to 550 mg/L when the cultures of Artemisia annua L hairy root were elicited with a homogenate of Aspergillus oryzae.

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Authors and Affiliations

  1. State Key Laboratory of Biochemical Engineering , Institute of Chemical Metallurgy, Chinese, Academy of Sciences, Beijing, 100080, China

    C.Z. Liu, Y.C. Wang & F. Ouyang

  2. Institute of Botany , Chinese Academy of Sciences, Beijing, 100093, China

    H.C. Ye & G.F. Li

Authors
  1. C.Z. Liu
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  2. Y.C. Wang
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  3. F. Ouyang
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  4. H.C. Ye
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  5. G.F. Li
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Liu, C., Wang, Y., Ouyang, F. et al. Production of artemisinin by hairy root cultures of Artemisia annua L. Biotechnology Letters 19, 927–929 (1997). https://doi.org/10.1023/A:1018362309677

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  • DOI: https://doi.org/10.1023/A:1018362309677

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