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Coulometric Determination of Purine Alkaloid Series with Electrogenerated Chlorine

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Abstract

In acid solution, caffeine, theobromine, and theophylline are rapidly and quantitatively oxidized with electrogenerated chlorine in a stoichiometric ratio of 2 : 5 to give alloxan and urea. Procedures for the coulometric determination of microgram amounts of caffeine, theophylline, and theobromine in model solutions, caffeine in tea and coffee samples, and caffeine and theophylline in some pharmaceutical preparations were developed.

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Authors and Affiliations

  1. Chuvash State University, Moskovskii pr. 15, Cheboksary, Chuvashia, 428015, Russia

    N. N. Chernysheva

  2. Kazan State University, ul. Kremlevskaya 18, Kazan, Tatarstan, 420008, Russia

    I. F. Abdullin & G. K. Budnikov

Authors
  1. N. N. Chernysheva
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  2. I. F. Abdullin
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  3. G. K. Budnikov
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Chernysheva, N.N., Abdullin, I.F. & Budnikov, G.K. Coulometric Determination of Purine Alkaloid Series with Electrogenerated Chlorine. Journal of Analytical Chemistry 56, 663–665 (2001). https://doi.org/10.1023/A:1016700507565

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  • DOI: https://doi.org/10.1023/A:1016700507565

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