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Polymorphic Markers of the Angiotensin and Angiotensin-Converting Enzyme Genes in Yakuts: A Lack of Association with Blood Pressure

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Abstract

Allele frequency distributions of the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene and the M235T polymorphism of the angiotensinogen gene was studied in a random sample of the indigenous population of the Sakha Republic. The allelic variants of these genes did not showed an association with blood pressure in Yakuts.

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Authors and Affiliations

  1. Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, 123182, Russia

    O. V. Miloserdova, P. A. Slominsky & S. A. Limborskaya

  2. Institute of Health, Yakutsk, 677891, Sakha Republic, Russia

    L. A. Tarskaya

  3. Department of Anthropology, Northwestern University, Evanston, Illinois, IL 27599, United States

    M. Sorensen

  4. Medical Genetic Research Center, Russian Academy of Medical Sciences, Moscow, 115478, Russia

    V. A. Spitsyn

Authors
  1. O. V. Miloserdova
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  2. P. A. Slominsky
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  3. L. A. Tarskaya
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  4. M. Sorensen
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  5. V. A. Spitsyn
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  6. S. A. Limborskaya
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Miloserdova, O.V., Slominsky, P.A., Tarskaya, L.A. et al. Polymorphic Markers of the Angiotensin and Angiotensin-Converting Enzyme Genes in Yakuts: A Lack of Association with Blood Pressure. Russian Journal of Genetics 37, 584–586 (2001). https://doi.org/10.1023/A:1016639320187

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  • DOI: https://doi.org/10.1023/A:1016639320187

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