Abstract
A series of isodithiobiurets, dithiobiurets, and dithiazoles was synthesized and tested for biological activity. Generally, the compounds potentiated the hypnosis induced by pentobarbitone (50 mg/kg ip) in albino mice and exhibited antifungal and insecticidal activity against Fusarium oxysporum and Periplanata americana, respectively. Some compounds showed anticonvulsant and analgesic activity in albino rats.
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Pandeya, S.N., Kumar, A., Singh, B.N. et al. Synthesis and Biological Activity of Isodithiobiurets, Dithiobiurets, and Dithiazoles. Pharm Res 4, 321–326 (1987). https://doi.org/10.1023/A:1016449321049
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DOI: https://doi.org/10.1023/A:1016449321049