Abstract
Purpose: To report on a case of Crohn's disease and unilateral retinal vasculitis, branch retinal artery occlusion and subsequent retinal neovascularization. Methods: We examined a 38-year-old woman with severe left visual loss and biopsy-proven Crohn's disease diagnosed four years prior to the ocular involvement. A Heidelberg scanning laser ophthalmoscope was used for fundus fluorescein angiography and indocyanine green angiography. Retinal neovascularization was detected during the follow-up. Results: Successful regression of retinal neovascularization was achieved after argon green laserpanretinal photocoagulation in addition to oral steroid and salazopyrine. Conclusion: Retinal vascular involvement is a rare ocular feature of Crohn's disease and may result in retinal neovascularization that may necessitate prompt laser photocoagulation.
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References
Hopkins DJ, Horan E, Burton IL, Clamp SE, De Dombal FT, Goligher JC. Ocular disorders in a series of 332 patients with Crohn's disease. Br J Ophthalmol 1974; 58: 732-737.
Greenstein AJ, Janowitz HD, Sachar DB. The extraintestinal complications of Crohn's disease and ulcerative colitis: A study of 700 patients. Medicine: 1976; 55: 401-412.
Petrelli AE, Mc Kinley M, Tronsale FJ. Ocular manifestations of inflammatory bowel disease. Ann Ophthalmol 1982; 14: 356-360.
Danzi JT. Extraintestinal manifestations of idiopathic inflammatory bowel disease. Arch Intern Med 1988; 148: 297-302.
Salmon JF, Wright JP, Murray ADN. Ocular inflammation in Crohn' s disease. Ophthalmology 1991; 98: 480-484.
Soukiasian SH, Foster S, Raizman MG. Treatment strategies for scleritis and uveitis associated with inflammatory bowel disease. Am J Ophthalmol 1994; 118: 601-611.
Macoul KL. Ocular changes in granulomatous ileocolitis. Arch Ophthalmol 1970; 84: 95-97.
Ernst BB, Lowder CY, Meisler DM, Gutman FA. Posterior segment manifestations of inflammatory bowel disease. Ophthalmology 1991; 98: 1272-1280.
Schneiderman JH, Sharpe JA, Sutton DM. Cerebral and retinal vascular complications of inflammatory bowel disease. Ann Neurol 1979; 5: 331.
Zegarra H, Gutman FA, Zabov N, Carim M. Partial occlusion of the central retinal vein. Am J Ophthalmol 1983; 96: 330-337.
Sedwick LA, Klingele JG, Burde RM, Behrens MM. Optic neuritis in inflammatory bowel disease. J Clin Neurol Ophthalmol 1984; 4: 3-6.
Duker JS, Brown GC, Brooks L. Retinal vasculitis in Crohn' s disease. Am J Ophthalmol 1987; 103: 664-668.
Ruby AJ, Jampol LM. Crohn's disease and retinal vascular disease. Am J Ophthalmol 1990; 110: 349-353.
Garcia-Diaz M, Mira M, Nevado L, Galvan A, Berenguer A, Bureo JC. Retinal vasculitis associated with Crohn's disease. Postgrad Med J 1995; 71: 170-172.
Sykes SO, Horton JL. Steroid-responsive retinal vasculitis with a frosted branch appearance in Crohn's disease. Retina 1997; 17: 451-454.
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Saatci, O.A., Koçak, N., Durak, İ. et al. Unilateral retinal vasculitis, branch retinal artery occlusion and subsequent retinal neovascularization in Crohn's disease. Int Ophthalmol 24, 89–92 (2001). https://doi.org/10.1023/A:1016351800466
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DOI: https://doi.org/10.1023/A:1016351800466