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Alkaloids of Aconitum coreanum. X. Curare-Like Activity-Structure Relationship

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Chemistry of Natural Compounds Aims and scope

Abstract

The biological activity of 11 alkaloids isolated from Aconitum coreanum was studied. The compounds exhibit myorelaxant activity. Isoatisine and coryphine, which contain oxazolidine rings, are the most active. N-Oxides of 2-isobutyryl-14-hydroxyhetisine and 2-isobutyryl-13-acetyl-14-hydroxyhetisine are least active.

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Authors and Affiliations

  1. S.Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent

    F. N. Dzhakhangirov & I. A. Bessonova

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  1. F. N. Dzhakhangirov
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  2. I. A. Bessonova
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Dzhakhangirov, F.N., Bessonova, I.A. Alkaloids of Aconitum coreanum. X. Curare-Like Activity-Structure Relationship. Chemistry of Natural Compounds 38, 74–77 (2002). https://doi.org/10.1023/A:1015742001422

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  • DOI: https://doi.org/10.1023/A:1015742001422

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