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Protective Effect of Biolan during Ischemic Damages to Cultured Cerebellar Granular Cells

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Abstract

Biolan containing carnosine and delta sleep-inducing peptide produced a protective effect on cerebellar granular cells from 7-day-old rats exposed in culture to ischemia (oxygen and glucose deprivation) and cytotoxic influence of glutamate. These results indicate that Biolan holds much promise for correction of ischemic brain damages in clinical practice.

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Authors and Affiliations

  1. Institute of Brain Research, Russian Academy of Medical Sciences, Russia

    L. G. Khaspekov, T. P. Klyushnik, A. M. Dupin, A. A. Lyzhin & M. V. Bezrukov

  2. Institute of Clinical Psychiatry, Research Center for Mental Health, Russian Academy of Medical Sciences, Moscow

    L. G. Khaspekov, T. P. Klyushnik, A. M. Dupin, A. A. Lyzhin & M. V. Bezrukov

Authors
  1. L. G. Khaspekov
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  2. T. P. Klyushnik
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  3. A. M. Dupin
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  4. A. A. Lyzhin
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  5. M. V. Bezrukov
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Khaspekov, L.G., Klyushnik, T.P., Dupin, A.M. et al. Protective Effect of Biolan during Ischemic Damages to Cultured Cerebellar Granular Cells. Bulletin of Experimental Biology and Medicine 133, 136–138 (2002). https://doi.org/10.1023/A:1015586403220

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  • DOI: https://doi.org/10.1023/A:1015586403220

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