Abstract
The cell extracts (i.e., intracellular metabolites) and culture liquids (i.e., extracellular metabolites) of microorganisms isolated from various ecotopes were found to inhibit the catalase activity of Staphylococcus aureus ATCC 6538 P, which resulted in a considerable inhibition of the growth of metabolite-treated S. aureus cells by hydrogen peroxide. The inhibitory effect of microbial metabolites on S. aureus catalase can be considered as a mechanism of intercellular interactions responsible for the formation of microbiocenoses.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
REFERENCES
Bukharin, O.V., Persistentsiya patogennykh bakterii(Persistence of Pathogenic Bacteria), Moscow: Meditsyna, 1999.
Pahlson, C. and Larsson, P.G., The Ecologically Wrong Vaginal Lactobacilli, Med. Hypotheses, 1991, vol. 36, pp. 125-130.
Usvyatsov, B.Ya., Lysozyme and Antilysozyme Activities of Pathogenic Cocci, Doctoral (Med.) Dissertation, Leningrad, 1986.
Mitrokhin, S.D. and Ivanov, A.A., Significance of Fecal Carbonic Acids in the Diagnosis of Dysbacteriosis, Mikrobiol. Zh., 1995, no. 4, pp. 99-101.
Egorov, N.S. and Baranova, I.P., Bacteriocins: Formation, Properties, and Applications, Antibiot. Khimioter.,1999, vol. 44, no. 6, pp. 33-40.
Hillier, S.L., Krohn, M.A., Klebanoff, S.J., and Eschenbach, D.A., The Relationship of Hydrogen Peroxide-producing Lactobacilli to Bacterial Vaginosis and Genital Microflora in Pregnant Women, Obstet. Gynecol., 1992, vol. 79, no. 3, pp. 369-373.
Smirnova, G.V., Muzyka, N.G., Glukhovchenko, M.N., and Oktyabr’skii, O.N., Hydrogen Peroxide Modulates the Intracellular Levels of Thiols and Potassium in Escherichia coliCells, Mikrobiologiya, 1998, vol. 67, no. 5, pp. 594-600.
Menendez, M.C., Ainsa, J.A., Martin, C., and Garcia, M.J., katGIand katGIIEncode Two Different Catalases-Peroxidases in Mycobacterium fortuitum, J. Bacteriol., 1997, vol. 179(22), pp. 6880-6886.
Mobley, H.L., Helicobacter pyloriFactors Associated with Disease Development, Gastroenterology,1997, vol. 113(6), pp. 21-28.
Zemser, R.B. and Martin, S.E., Heat Stability of Virulence-associated Enzymes from Listeria monocytogenesSLCC 5764, J. Food Prot., 1998, vol. 61(7), pp. 899-902.
Bergey’s Manual of Systematic Bacteriology, 9th ed., Holt, J.G. et al., Eds., Baltimore: Williams & Wilkins
Bukharin, O.V., Cherkasov, S.V., Sgibnev, A.V., Zabirova, T.M., and Ivanov, Yu.B., The Effect of Microbial Metabolites on the Catalase Activity and Growth of Staphylococcus aureus6538 P, Byull. Eksp. Biol., 2000, vol. 130, no. 7, pp. 80-82.
Ashmarin, I.P. and Vorob’ev, A.A., Statisticheskie metody v mikrobiologicheskikh issledovaniyakh(Statistical Methods in Microbiological Investigations), Leningrad, 1962.
Parshuta, L.I., Formation of Nasal Microbial Cenoses in Staphylococcus Carriers, Cand. Sci. (Med.) Dissertation, Orenburg, 1998.
Sokolova, K.Ya., Savel’eva, I.V., Popova, I.V., et al., Autoflora cheloveka v norme i patologii i ee korrektsiya(Autogenous Human Microflora in Norm and Pathology and Its Correction), Blokhina, I.N., Ed., Gor’kii, 1998, pp. 144-148.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Bukharin, O.V., Sgibnev, A.V., Cherkasov, S.V. et al. The Effect of the Intra- and Extracellular Metabolites of Microorganisms Isolated from Various Ecotopes on the Catalase Activity of Staphylococcus aureus ATCC 6538 P. Microbiology 71, 154–157 (2002). https://doi.org/10.1023/A:1015185818509
Issue Date:
DOI: https://doi.org/10.1023/A:1015185818509