Abstract
The reactions of substituted anilines with chloroacetamide and sulfur in the presence of triethylamine afforded monothiooxamides. When treated with K3Fe(CN)6, the latter underwent cyclization to form 2-carbamoylbenzothiazoles. The reactions were accompanied by the formation of the corresponding thiooxanilic acids, which also underwent cyclization to form benzothiazole-2-carboxylic acids.
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Yarovenko, V.N., Stoyanovich, F.M., Zolotarskaya, O.Y. et al. New approach to the synthesis of 2-carbamoylbenzothiazoles. Russian Chemical Bulletin 51, 144–147 (2002). https://doi.org/10.1023/A:1015082318393
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DOI: https://doi.org/10.1023/A:1015082318393