Abstract
o-Alkyl derivatives of N-acetylaminobenzo-12-crowns-4 4a—f were prepared by Pd—Cu-catalyzed alkynylation of 5"-N-acetylamino-4"-iodobenzo-12-crown-4 (2). Cyclization of compounds 4a—f afforded the corresponding substituted 5,6-indolo-12-crowns-4 5a—c.
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Klyatskaya, S.V., Tretyakov, E.V. & Vasilevsky, S.F. Synthesis of 5,6-indolo-12-crown-4 ethers. Russian Chemical Bulletin 51, 135–138 (2002). https://doi.org/10.1023/A:1015078217485
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DOI: https://doi.org/10.1023/A:1015078217485