Abstract
The available investigations on the structure and properties of the enzyme organophosphate hydrolase exhibiting catalytic activity with respect to orthophosphates are reviewed. Recent data on the mechanism of enzymatic hydrolysis of paraoxon are surveyed. The role of two metal ions involved in the enzyme active site is considered. The substrate specificity and the influence of various inhibitors on the kinetic characteristics of the enzyme are discussed.
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Efremenko, E.N., Sergeeva, V.S. Organophosphate hydrolase — an enzyme catalyzing degradation of phosphorus-containing toxins and pesticides. Russian Chemical Bulletin 50, 1826–1832 (2001). https://doi.org/10.1023/A:1014377912147
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DOI: https://doi.org/10.1023/A:1014377912147