Abstract
Morphometric analysis revealed no signs of myocardial hypertrophy at the tissue and ultrastructural levels in 3-week-old NISAG rat pups reared by normotensive Wistar females. The severity of myocardial hypertrophy in these animals aging 6 months was similar to that in NISAG rats reared by natural mothers. However, raising conditions during the early ontogeny form compensatory structural changes in the myocardium of rats with genetically determined hypertension.
Similar content being viewed by others
REFERENCES
G. G. Avtandilov, Medical Morphometry[in Russian], Moscow (1990).
S. Ya. Amstislavskii, N. K. Popova, Yu. E. Tomilova, et al., Ros. Fiziol. Zh., 84, No. 8, 783-786 (1998).
M. D. Shmerling, E. E. Filyushina, I. M. Korostyshevskaya, et al., Byull. Eksp. Biol. Med., 122, No. 9, 271-283 (1996).
M. D. Shmerling, E. E. Filyushina, I. M. Korostyshevskaya, et al., Byull. Sib. Otd. Ros. Akad. Med. Nauk, No. 2, 91-94 (1997).
P. Anversa, M. Melissari, C. Beghi, and G. Olivetti, Am. J. Physiol., 246, H739-H749 (1984).
M. A. Cierpial, M. Konarska, and R. McCarty, Health Psychol., 7, No. 2, 125-135 (1988).
M. A. Cierpial and R. McCarty, Behav. Neural. Biol., 56, No. 3, 262-270 (1991).
I. Gouldsborough and N. Ashton, Clin. Exp. Pharmacol. Physiol., 25, No. 12, 1024-1031 (1998).
I. Gouldsborough, V. Black, I. T. Johnson, and N. Ashton, Acta Physiol. Scand., 162, No. 1, 107-114 (1998).
R. McCarty, M. A. Cierpial, C. A. Murphy, et al., Experientia, 48, No. 4, 315-322 (1992).
M. M. Meyers, S. A. Brunelli, J. M. Squire, et al., Dev. Psychobiol., 22, No. 1, 29-53 (1989).
J. L. Rose and R. McCarty, Physiol. Behav., 56, No. 5, 901-906 (1994).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Korostyshevskaya, I.M., Maksimov, V.F., Markel', A.L. et al. Peculiarities of Myocardial Structure in Rats with Hereditary Hypertension Reared by Normotensive Females. Bulletin of Experimental Biology and Medicine 132, 895–897 (2001). https://doi.org/10.1023/A:1013191306479
Issue Date:
DOI: https://doi.org/10.1023/A:1013191306479