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Bioactive response of Ag-doped tape cast Bioglass® 45S5 following heat treatment

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Abstract

The suitability of Bioglass® 45S5 to the tape casting process and the ability of the glass to retain in vitro bioactivity following heat treatment to increase strength has been established. In this research, tape cast Bioglass® was doped with silver prior to heat treatment in an effort to impart antimicrobial properties. The effect of initial dopant concentration and processing temperature was investigated. FTIR confirmed the presence of well established hydroxyapatite (HA) surface layers on Ag-doped tape cast Bioglass® following heat treatment and simulated body fluid (SBF) immersion. Solution analysis revealed the release of silver ion in concentrations similar to those reported in the literature to have antimicrobial effects. Additionally, mercury porosimetry was used to determine that silver enhanced the densification process relative to that of undoped tape cast Bioglass®. Ag-doped tape cast and sintered Bioglass® (TCSBG) appears promising for use in situations requiring rapid surface HA formation and antimicrobial properties.

© 2001 Kluwer Academic Publishers

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References

  1. T. N. Kim, Q. L. Feng, J. Q. Kim, J. Wu, H. Wang, G. C. Chen and F. Z. Cui, J. Mater. Sci. Mater. Med. 9 (1998) 129.

    Google Scholar 

  2. S. B. Sant, K. S. Gill and R. E. Burrell, Scripta Metall. 41 (1999) 1333.

    Google Scholar 

  3. M. Kawashita, S. Tsuneyama, F. Miyaji, T. Kokubo, H. Kozuka and K. Yamamoto, Biomaterials 21 (2000) 393.

    Google Scholar 

  4. Ch. Y. Li, Z. Wan, J. Wang, Y. L. Wang, X. Q. Jiang and L. M. Han, Carbon 36 (1997) 61.

    Google Scholar 

  5. M. Rivera-Garza, M. T. OlguÍn, I. GarcÍa-Sosa, D. AlcÁntara and G. RodrÍguez-Fuentes, Microporous and Mesoporous Materials 39 (2000) 431.

    Google Scholar 

  6. M. Bellantone, N. J. Coleman and L. L. Hench, J. Biomed. Mater. Res. 51 (2000) 484.

    Google Scholar 

  7. L. L. Hench, R. J. Splinter, W. C. Allen and T. K. Greenlee, J. Biomed. Mater. Res. Sym. 2 (1971) 117.

    Google Scholar 

  8. D. C. Clupper, J. J. Mecholsky, Jr., G. P. Latorre and D. C. Greenspan, J. Biomed. Mater. Res. 57 (2001) 532.

    Google Scholar 

  9. D. C. Clupper, J. J. Mecholsky, Jr., G. P. Latorre and D. C. Greenspan, J. Mater. Sci. Lett. 20 (2001) 959.

    Google Scholar 

  10. T. Kokubo, in “An Introduction to Bioceramics”, edited by L. L. Hench and J. Wilson (World Scientific, Singapore, 1993) p. 75.

    Google Scholar 

  11. M. R. T. Filgueiras, G. Latorre and L. L. Hench. J. Biomed. Mater. Res. 27 (1993) 1485.

    Google Scholar 

  12. L. L. Hench. ibid. 40 (1998) 511.

    Google Scholar 

  13. M. Aydin, I. Gunay, A. Pelit and M. S. Serin, ibid. 38 (1997) 49.

    Google Scholar 

  14. J.-P. Guggenbichler, M. Boswald, S. Lugauer and T. Krall, Infection 27 (1999) S16.

    Google Scholar 

Download references

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Authors and Affiliations

  1. Centre for Tissue Engineering, Department of Materials, Imperial College of Science, Technology and Medicine, Prince Consort Road, London, SW7 2BP, UK

    D. C. Clupper & L. L. Hench

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  1. D. C. Clupper
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  2. L. L. Hench
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Clupper, D.C., Hench, L.L. Bioactive response of Ag-doped tape cast Bioglass® 45S5 following heat treatment. Journal of Materials Science: Materials in Medicine 12, 917–921 (2001). https://doi.org/10.1023/A:1012836426866

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