Skip to main content
SpringerLink
Log in

Synthesis and study of the mutagenic activity of di(indeno[2,1-b]indolyl)- and di(indeno[2,1-b]pyrrolyl)methanes and -dimethylsilanes

  • Published:
Russian Chemical Bulletin Aims and scope

Abstract

Dihetaryldimethylsilanes and dihetarylmethanes containing indeno[2,1-b]indolyl and indeno[2,1-b]pyrrolyl fragments were synthesized. Their mutagenic activity was tested according to Ames with standard test strains Salmonella typhimurium TA 1537, TA 98, and TA 100.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. W. Vance and D. Levin, Environ. Mutagen, 1984, 6, 797.

    Google Scholar 

  2. D. Brown, P. Graupner, M. Sainsbury, and H. Shertzer, Tetrahedron, 1991, 47, 4383.

    Google Scholar 

  3. G. Kempter, M. Schwalba, W. Stoss, and K. Walter, J. Prakt. Chem., 1962, 18, 39.

    Google Scholar 

  4. Buu-Hoi and R. Royer, Bull. Soc. Chim. Fr., 1947, 14, 812.

    Google Scholar 

  5. G. N. Zhungietu, N. N. Suvorov, and A. N. Kost, in Novye preparativnye sintezy v indol'nom ryadu [New Preparative Syntheses in the Indole Series], Shtiintsa, Chisinau, 1983, 35 (in Russian).

  6. D. M. Quizon-Colquit and T. D. Lash, J. Heterocycl. Chem., 1993, 30, 477.

    Google Scholar 

  7. C. F. Charles and H. Adkins, J. Am. Chem. Soc., 1933, 55, 4169.

    Google Scholar 

  8. P. V. Ivchenko and I. E. Nifant'ev, Zh. Org. Khim., 1998, 34, 9 [Russ. J. Org. Chem., 1998, 34 (Engl. Transl.)].

    Google Scholar 

  9. L. Resconi, D. Balboni, G. Baruzzi, C. Fiori, and S. Guidotti, Organometallics, 2000, 19, 420.

    Google Scholar 

  10. S. K. Abilev and G. G. Poroshenko, in Toksikologiya. Uskorennye metody prognozirovaniya mutagennykh i blastomogennykh svoistv khimicheskikh soedinenii [Toxycology, Accelerated Tests for the Mutagenic and Blastogenic Properties of Chemical Compounds], VINITI, Moscow, 1986, 14, 174 (in Russian).

    Google Scholar 

  11. D. M. Maron and B. N. Ames, Mutat. Res., 1983, 113, 173.

    Google Scholar 

  12. Organic Solvents. Physical Properties and Methods of Purification, Ed. A. Weissberger, Interscience Publ., New York-London, 1955.

    Google Scholar 

  13. J. Armit and R. Robinson, J. Chem. Soc., 1922, 121, 838.

    Google Scholar 

  14. S. Gabriel and R. Stelsner, Chem. Ber., 1896, 29, 2605.

    Google Scholar 

  15. K. Patsidis, H. G. Alt, W. Millius, and S. J. Palackal, J. Organomet. Chem., 1996, 509, 63.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Chemistry, Leninskie Gory, M. V. Lomonosov Moscow State University, 119899, Moscow, Russian Federation

    I. E. Nifant"ev, I. A. Kashulin & V. V. Bagrov

  2. N. I. Vavilov Institute of General Genetics, Russian Academy of Science, 3 ul. Gubkina, 119991, Moscow, Russian Federation

    S. K. Abilev & I. K. Lyubimova

Authors
  1. I. E. Nifant"ev
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. I. A. Kashulin
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. V. V. Bagrov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. S. K. Abilev
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. I. K. Lyubimova
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nifant"ev, I.E., Kashulin, I.A., Bagrov, V.V. et al. Synthesis and study of the mutagenic activity of di(indeno[2,1-b]indolyl)- and di(indeno[2,1-b]pyrrolyl)methanes and -dimethylsilanes. Russian Chemical Bulletin 50, 1439–1445 (2001). https://doi.org/10.1023/A:1012745325790

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1012745325790

Search

Navigation