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Synthesis of Substituted 2-Aryl- and 2-Hetarylimidazo[4,5-d]pyridazines

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Abstract

Substituted 2-aryl- and 2-hetarylimidazo[4,5-d]pyridazines were synthesized by oxidative cyclization in the presence of sulfur of 4,5-diamino-6-methylpyridazin-3-one with substituted arene(hetarene)carbaldehydes or heterocyclic compounds having an activated methyl group.

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REFERENCES

  1. FRG Patent Appl. no. 3 347 290, 1985; Ref. Zh., Khim., 1986, no. 13O79 P.

  2. FRG Patent Appl. no. 3 445 299, 1986; Ref. Zh., Khim., 1987, no. 3O147 P.

  3. Gerhardt, G.A., Aldous, D.L., and Castle, R.N., J. Heterocycl. Chem., 1965, vol. 2, no. 34, pp. 247-252.

    Google Scholar 

  4. Itai, T. and Suzuki, S., Chem. Pharm. Bull., 1960, vol. 8, no. 11, pp. 999-1004.

    Google Scholar 

  5. Yanai, M., Kinoshita, T., Takeda, S., Sadaki, H., and Watanabe, H., Chem. Pharm. Bull., 1970, vol. 18, no. 8, pp. 1685-1692.

    Google Scholar 

  6. Kenji, K., Hiromu, N., Yusha, O., Keizo, T., and Hirohisa, O., J. Heterocycl. Chem., 1984, vol. 21, no. 5, pp. 1249-1254.

    Google Scholar 

  7. Yutilov, Yu.M., Shcherbina, L.I., and Efremenko, A.F., Khim. Geterotsikl. Soedin., 1989, no. 7, pp. 940-947.

    Google Scholar 

  8. Yutilov, Yu.M. and Shcherbina, L.I., Khim. Geterotsikl. Soedin., 1987, no. 5, pp. 639-645.

    Google Scholar 

  9. Yutilov, Yu.M., Stetsenko, L.V., and Shcherbina, L.I., Abstracts of Papers, XVII Ukrainskaya konferentsiya po organicheskoi khimii (XVIIth Ukrainian Conf. on Organic Chemistry), Kharkov, 1995, part 1, p. 91.

  10. Lespagnol, A. and Deprey, J., Bull. Soc. Chim. Fr., 1961, no. 3, pp. 606-610.

    Google Scholar 

  11. Overend, W.G. and Wiggins, L.F., J. Chem. Soc., 1947, no. 3, pp. 239-244.

    Google Scholar 

  12. Singh, B., Heterocycles, 1984, vol. 22, no. 8, pp. 1801-1804.

    Google Scholar 

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Authors and Affiliations

  1. Ukrainian National Academy of Sciences, Litvinenko Institute of Physical Organic and Coal Chemistry, ul. R. Luxemburg 70, Donetsk, 83114, Ukraine

    S. V. Gres'ko, N. N. Smolyar & Yu. M. Yutilov

Authors
  1. S. V. Gres'ko
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  2. N. N. Smolyar
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  3. Yu. M. Yutilov
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Gres'ko, S.V., Smolyar, N.N. & Yutilov, Y.M. Synthesis of Substituted 2-Aryl- and 2-Hetarylimidazo[4,5-d]pyridazines. Russian Journal of Organic Chemistry 37, 1026–1029 (2001). https://doi.org/10.1023/A:1012490919797

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