Abstract
Any inflammation, infectious or noninfectious, is characterized by consecutive changes in the parameters of the total blood counts, including subpopulations of lymphocytes. The magnitude of these changes is determined by the intensity and extent of the inflammation. In patients with active inflammation (without a history of immune insufficiency) an active antibacterial therapy by surgical treatment of abscesses and by antibiotics or sulfanilamides results in a normal development and termination of the inflammation. Under intoxication of the body, the inflammation course is decelerated; and detoxification activates the immune system, normalizes the inflammation course, and promotes its termination. In these cases the use of nonspecific immunity modifiers fails to optimize the course of inflammation. On the contrary, the use of nonspecific immunity modifiers in patients with a history of immune insufficiency often activates the inflammation and promotes its effective termination.
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Ponyakina, I.D., Robustova, T.G., Lokhvitskii, S.V. et al. Activation of the Immune System in Acute Inflammatory Disease. Human Physiology 27, 488–493 (2001). https://doi.org/10.1023/A:1010983307778
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DOI: https://doi.org/10.1023/A:1010983307778