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Improved paclitaxel accumulation in cell suspension cultures of Taxus chinensis by brassinolide

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Abstract

When brassinolide was added at 17 ng l−1 to Taxus chinensis cell suspension cultures, the paclitaxel content was increased by over 100% to 580 μg g−1 dry weight. Brassinolide may therefore be a novel regulator of paclitaxel biosynthesis.

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Authors and Affiliations

  1. School of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China

    Xin Zang, Xing-Guo Mei, Chang-He Zhang, Cui-Tao Lu & Tie Ke

Authors
  1. Xin Zang
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  2. Xing-Guo Mei
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  3. Chang-He Zhang
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  4. Cui-Tao Lu
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  5. Tie Ke
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Correspondence to Xin Zang.

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Zang, X., Mei, XG., Zhang, CH. et al. Improved paclitaxel accumulation in cell suspension cultures of Taxus chinensis by brassinolide. Biotechnology Letters 23, 1047–1049 (2001). https://doi.org/10.1023/A:1010589304749

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