Skip to main content
SpringerLink
Log in

Improved HPLC method for taxol determination with A12O3 solid-phase extraction

  • Published:
Biotechnology Techniques

Abstract

The closely eluting compounds of taxol, cephalomannine and N-debenzoyl-N-phenylacetyl taxol, were successfully removed from a sample of Taxus yunnanis by γ-Al2 O3 solid-phase extraction. A sensitive, selective, rapid and accurate C18 HPLC method for taxol determination was established. © Rapid Science Ltd. 1998

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Kopycki, W.J., Elsohly, H.N., and McCkesney (1994). J. Liq. Chromatog. 17:2569-2591

    Google Scholar 

  • Mattina, M.J.I., and MacEachern G.J. (1994). J. Chromatogr. A 679:269-275

    Google Scholar 

  • Rowinsky, E.R., Cazenave, L.A., and Donehower, R.C. (1990). J. Nat. Cancer Inst. 82:1247-1259

    Google Scholar 

  • Shao, L.K., and David, C.L. (1997). Anal. Chem. 69:2008-2016

    Google Scholar 

  • Wani, M.C., Taylor, H.L., Wall, M.E., Coggon, P., and McPhail, A.T. (1971). J. Am. Chem. Soc. 93:2325-2327

    Google Scholar 

  • Witherup, K.M., Look, S.A., Stasko, M.W., McCloud, T.G., Issaq, H.J., and Muschik, G.M. (1989). J. Liq. Chromatog. 12:2117-2132

    Google Scholar 

  • Wu, D.R., Lohse, K., Hellen C., and Greenblatt (1995). J. Chromatogr. A 702:233-241

    Google Scholar 

  • Wu, Y.G., and Zhu, W.H.. (1997). J. Liq. Chrom. Rel. Technol. 20:3147-3154

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Biochemical Engineering, Dalian University of Technology, Dalian, China

    Zhang Zhiqiang, Tian Guilian & Xu Jianfeng

  2. State Key Laboratory of Biochemical Engineering, Institute of Chemical Metallurgy, Chinese Academy of Science, Beijing, China

    Wei Xingui & Su Zhiguo

Authors
  1. Zhang Zhiqiang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Wei Xingui
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Tian Guilian
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Xu Jianfeng
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Su Zhiguo
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zhiqiang, Z., Xingui, W., Guilian, T. et al. Improved HPLC method for taxol determination with A12O3 solid-phase extraction. Biotechnology Techniques 12, 633–636 (1998). https://doi.org/10.1023/A:1008888231333

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1008888231333

Keywords

Search

Navigation