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Does the Latency Associated Transcript (LAT) of Herpes Simplex Virus (HSV) Function as a Ribozyme during Viral Reactivation?

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Abstract

The latency associated transcript (LAT) of herpes simplex virus (HSV) appears to exist as an RNA molecule only. This phenomenon is consistent with the concept of functioning at an RNA level, and several lines of evidence suggest that the LAT may be a ribozyme. This provides an insight into understanding the role of LAT during HSV reactivation.

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Authors and Affiliations

  1. Institute of Microbiology and Immunology (IMI), School of Life Science, National Yang-Ming University (NYMU), Taipei, Taiwan, People’s Republic of China, 112 e-mail

    Eric Ka-Wai Hui & Szecheng J. Lo

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  1. Eric Ka-Wai Hui
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  2. Szecheng J. Lo
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Ka-Wai Hui, E., Lo, S.J. Does the Latency Associated Transcript (LAT) of Herpes Simplex Virus (HSV) Function as a Ribozyme during Viral Reactivation?. Virus Genes 16, 147–148 (1998). https://doi.org/10.1023/A:1007937521771

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  • DOI: https://doi.org/10.1023/A:1007937521771

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