Abstract
The association and distribution of HLA antigens in, and the contribution of genetic susceptibility to enuresis, were investigated in the present study. HLA-DQ1 was found in 35 of the 45 patients (77.7%) in the study group, but in only 19 of the 50 cases (38%) in the control group (p<0.05, n = 2.03). The association between HLA-DQ1 and nocturnal enuresis demonstrated in this study may lead to further identification of related chromosomes and loci for various subgroups of nocturnal enuresis, and the identification and differentiation of these subgroups may have direct implications for rational trials of therapy.
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Dündaröz, M.R., Sarici, S.Ü., Okutan, V. et al. HLA Antigens in Nocturnal Enuresis. Int Urol Nephrol 31, 811–815 (1999). https://doi.org/10.1023/A:1007110000169
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DOI: https://doi.org/10.1023/A:1007110000169