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Copper(II) complexes of formyl- and acetylpyrazine N(4)- (2–methylpyridinyl)-, N(4)-(2–ethylpyridinyl)- and N(4)-methyl- (2–ethylpyridinyl)thiosemicarbazones

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Abstract

The title complexes of general formula [Cu(HL)Cl2] or [Cu(L)Cl] were isolated from boiling EtOH. The thiosemicarbazones have been characterized by their 1H- and 13C-n.m.r., i.r. and electronic spectra. The i.r., electronic and e.s.r. spectra of the copper(II) complexes are compared with data on previously studied complexes. The antitumour and antiviral activities of the thiosemicarbazones and their complexes are discussed.

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References

  1. D. X. West, S. B. Padhye and P. B. Sonawane, Structure Bonding, 76, 1 (1991).

    CAS  Google Scholar 

  2. C. F. Bell, K. A. K. Lott and N. Hearn, Polyhedron, 6, 39 (1987).

    Article  CAS  Google Scholar 

  3. D. X. West, P. M. Ahrweiler, G. Ertem, J. P. Scovill, D. L. Klayman, J. L. Flippen-Anderson, R. Gilardi, C. George and L. K. Pannell, Transition Met. Chem., 10, 264 (1985); D. X. West and N. C. Lewis, Transition Met. Chem., 12, 365 (1987); D. X. West, C. S. Carlson, A. C. Whyte and A. E. Liberta, Transition Met. Chem., 15, 43 (1990); D. X.. West, R. D. Profilet and J. L. Hines, Transition Met. Chem., 13, 467 (1988); S. K. Jain, B. S. Garg, Y. K. Bhoon, D. L. Klayman and J. P. Scovill, Spectrochim. Acta, A, 41, 407 (1985); R. J. Butcher and D. X. West, Transition Met. Chem., 18, 449 (1993).

    Article  CAS  Google Scholar 

  4. S. K. Jain, B. S. Garg and Y. K. Bhoon, Spectrochim. Acta, A, 42, 959 (1986); D. X. West and N. C. Lewis, Transition Met. Chem., 13, 277 (1988); D. X. West, C. S., Carlson, C. P. Galloway, A. E. Liberta and C. R. Daniel, Transition Met. Chem., 15, 91 (1990); D. X. West, C. S. Carlson, A. E. Liberta, J. N. Albert and C. R. Daniel, Transition Met. Chem., 15, 341 (1990).

    Article  Google Scholar 

  5. Y. K. Bhoon, S. Mitra, J. P. Scovill and D. L. Klayman, Transition Met. Chem, 7, 264 (1982); Y. K. Bhoon, J. P. Scovill and D. L. Klayman, Indian J. Chem., 22A, 267 (1983); D. X. West, R. M. Makeever, J. P. Scovill and D. L. Klayman, Polyhedron, 3, 947 (1984); Y. K. Bhoon, D. L. Klayman and J. P. Scovill, Spectrochim. Acta, A, 40, 691 (1984); D. X. West, J. P. Scovill, J. V. Silverton and A. Bavoso, Transition Met. Chem., 11, 123 (1986); B. S. Garg, M. R. P. Kurup, S. K. Jain and Y. K. Bhoon, Transition Met. Chem., 13, 247 (1988); D. X. West and D. S. Galloway, Transition Met. Chem., 13, 410 (1988); D. X. West, D. S. Galloway and D. A. Case, Transition Met. Chem., 13, 415 (1988); D. X. West, C. S. Carlson, K. J. Bouck and A. E. Liberta, Transition Met. Chem., 16, 271 (1991); D. X. West, H. Gebremedhin, R. J. Butcher, J. P. Jasinski and A. E. Liberta, Polyhedron, 12, 2489 (1993).

    Article  CAS  Google Scholar 

  6. M. A. Malik and D. J. Phillips, J. Inorg. Nucl. Chem., 36, 2229 (1974); P. S. N. Reddy and B. V. Agarwala, Synth. React. Inorg. Met-org. Chem., 17, 585 (1987); D. X. West, D. L. Huffman, J. S. Saleda and A. E. Liberta, Transition Met. Chem., 16, 565 (1991); D. X. West, J. S. Saleda and A. E. Liberta, Transition Met. Chem., 17, 568 (1992) and refs therein.

    Article  CAS  Google Scholar 

  7. D. X. West, J. S. Ives, J. Krejci, M. M. Salberg, T. L. Zumbahlen, G. A. Bain, A. E. Liberta, J. Valdes-Martínez, S. Hernández-Ortega and R. A. Toscano, Polyhedron, 14, 2189 (1995) and refs therein.

    Article  CAS  Google Scholar 

  8. D. X. West, C. S. Carlson, A. E. Liberta and J. P. Scovill, Transition Met. Chem., 15, 383 (1990); D. X. West, M. A. Lockwood, A. E. Liberta, X. Chen and R. D. Willett, Transition Met. Chem., 18, 221 (1993); D. X. West, M. A. Lockwood, H. Gebremedhin, A. Castiñeiras and A. E. Liberta, Polyhedron, 12, 1887 (1993); C. Maichle, A. Castiñeiras, R. Carballo, D. X. West, H. Gebremedhin, M. A. Lockwood, C. E. Ooms and T. J. Romack, Transition Met. Chem., 20, 228 (1995); D. X. West, M. A. Lockwood, M. D. Owens and A. E. Liberta, Transition Met. Chem., 22, 366 (1997).

    Article  CAS  Google Scholar 

  9. D. X. West, A. C. Whyte, F. D. Sharif, H. Gebremedhin, and A. E. Liberta, Transition Met. Chem., 18, 238 (1993) and refs therein.

    Article  CAS  Google Scholar 

  10. D. X. West, A. M. Stark, G. A. Bain and A. E. Liberta, Transition Met. Chem., 21, 289 (1996) and refs therein.

    Article  CAS  Google Scholar 

  11. B. Holmberg and B. Psilanderhielm, J. Prakt. Chem., 82, 440 (1910).

    Article  Google Scholar 

  12. J. P. Scovill, Phosphorus, Sulfur, Silicon, Relat. Elem., 60, 15 (1991).

    CAS  Google Scholar 

  13. P. A. Goodson, O. R. Oki, J. Glerup and D. Hodgson, J. Am. Chem. Soc., 112, 6248 (1990).

    Article  CAS  Google Scholar 

  14. D. X. West, M. A. Lockwood and A. Castiñeiras, Transition Met. Chem., in press.

  15. K. R. Koch, J. Coord. Chem., 22, 289 (1991).

    Article  CAS  Google Scholar 

  16. J. Valdes-Martínez, S. Hernández-Ortega, D. X. West, J. S. Ives and G. A. Bain, unpublished observations.

  17. D. X. West, G. A. Bain, R. J. Butcher, J. P. Jasinski, Y. Li, R. Y. Pozdniakiv, J. Valdés-Martínez, R. A. Toscano and S. Hernández-Ortega, Polyhedron, 15, 665 (1996).

    Article  CAS  Google Scholar 

  18. D. X. West, H. Gebremedhin, R. J. Butcher, J. P. Jasinski and A. E. Liberta, Polyhedron, 12, 2489 (1993).

    Article  CAS  Google Scholar 

  19. D. X. West, C. E. Ooms, J. S. Saleda, H. Gebremedhin and A. E. Liberta, Transition Met. Chem., 19, 553 (1994).

    Article  CAS  Google Scholar 

  20. P. Sousa, J. A. Garcia-Vasquez and J. R. Masaguer, Transition Met. Chem., 9, 318 (1984); Synth. React. Inorg. Met-org. Chem., 15, 247 (1985); T. R. Rao, M. Sahay and R. C. Aggarwal, Synth. React. Inorg. Met-org. Chem., 15, 175 (1985).

    Article  Google Scholar 

  21. S. K. Senkupta, S. K. Sahni and R. N. Kapoor, Acta Chim. Acad Sci. Hungary, 104, 89 (1980).

    Google Scholar 

  22. G. DeVoto, M. Massacesi, R. Pinna and G. Ponticelli, Spectrochim. Acta, A, 38, 725 (1982).

    Article  Google Scholar 

  23. S. F. Mason in A. R. Katvitzky (Ed.), Physical Methods in Hetero-cyclic Chemistry, Academic Press, New York, 1962, Vol. II, Ch. 7.

    Google Scholar 

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  1. Department of Chemistry, Illinois State University, Normal, IL, 67690–4160, USA

    Douglas X. West & Matthew D. Owens

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  1. Douglas X. West
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West, D.X., Owens, M.D. Copper(II) complexes of formyl- and acetylpyrazine N(4)- (2–methylpyridinyl)-, N(4)-(2–ethylpyridinyl)- and N(4)-methyl- (2–ethylpyridinyl)thiosemicarbazones. Transition Metal Chemistry 23, 87–91 (1997). https://doi.org/10.1023/A:1006966219867

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