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Correlation between the consumption of amino acids and the production of the antibiotic gallidermin by Staphylococcus gallinarum

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Abstract

The correlation between the consumption of amino acids and the production of the polypeptide antibiotic gallidermin by Staphylococcus gallinarum Tü 3928 was investigated by on-line determination of amino acids and pulse experiments. A prolonged production phase together with an increase in gallidermin formation of about 25% was obtained during pulse and fed-batch experiments with the amino acids glutamic acid, glycine, serine and threonine.

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Authors and Affiliations

  1. Mikrobiologisches Institut, Universität Tübingen, Auf der Morgenstelle 28, D-72076, Tübingen, Germany

    M. Kempf, U. Theobald & H.-P. Fiedler

Authors
  1. M. Kempf
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  2. U. Theobald
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  3. H.-P. Fiedler
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Kempf, M., Theobald, U. & Fiedler, HP. Correlation between the consumption of amino acids and the production of the antibiotic gallidermin by Staphylococcus gallinarum . Biotechnology Letters 21, 959–963 (1999). https://doi.org/10.1023/A:1005642711472

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  • DOI: https://doi.org/10.1023/A:1005642711472

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