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Effect of Epoxidation of Carbocyclic Double Bonds on Conformational Flexibility of 1(10)E,4E-Germacranolides

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Abstract

The effect of substitution of double bonds by epoxy groups in 1(10)E,4E-germacranolides is studied by molecular mechanics. The probabilities of forming conformers in the epoxy derivatives are determined. Barriers to possible conformational transitions are estimated

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Authors and Affiliations

  1. Institute of Phytochemistry, Ministry of Education and Science, Republic of Kazakhstan, Karaganda

    A. K. Kaldybaeva, T. T. Edil'baeva & K. M. Turdybekov

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  1. A. K. Kaldybaeva
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  2. T. T. Edil'baeva
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  3. K. M. Turdybekov
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Kaldybaeva, A.K., Edil'baeva, T.T. & Turdybekov, K.M. Effect of Epoxidation of Carbocyclic Double Bonds on Conformational Flexibility of 1(10)E,4E-Germacranolides. Chemistry of Natural Compounds 36, 497–500 (2000). https://doi.org/10.1023/A:1002839523655

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