Abstract
A Streptomyces strain UK10 was isolated from Ukrainian soil and identified by taxonomical studies as Streptomyces arenae var ukrainiana. HA-2-91 was isolated from the biomass of S. arenae var ukrainiana and is supposedly a polyene macrolide antibiotic belonging to the tetraene group. HA-2-91 showed promising antifungal activity (in vitro) against yeasts and filamentous fungi, including plant pathogens and dermatophytes and was found to be less toxic in mice than nystatin and rimocidin.
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Gupte, T., Naik, S. Isolation, taxonomic and fermentation studies on a new strain of Streptomyces arenae var ukrainiana producing a tetraene antibiotic. World Journal of Microbiology and Biotechnology 15, 545–552 (1999). https://doi.org/10.1023/A:1008981528959
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DOI: https://doi.org/10.1023/A:1008981528959