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Enhanced paclitaxel production induced by the combination of elicitors in cell suspension cultures of Taxus chinensis

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Abstract

Taxus chinensis suspension cells were cultured in the modified Gamborg's B5 medium. Addition of 50 mg chitosan l−1, 60 μM methyl jasmonate and 30 μM Ag+ resulted in the greatest paclitaxel production, at 25 mg l−1 in the cultures, being almost 40 times higher than that of the control culture, 10 times higher than that of the culture exposed to Ag+, 6 times higher than that of the culture elicited by chitosan and almost double that of the culture elicited by methyl jasmonate.

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Authors and Affiliations

  1. School of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China

    C.H. Zhang, X.G. Mei, L. Liu & L.J. Yu

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  1. C.H. Zhang
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  2. X.G. Mei
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  3. L. Liu
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  4. L.J. Yu
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Zhang, C., Mei, X., Liu, L. et al. Enhanced paclitaxel production induced by the combination of elicitors in cell suspension cultures of Taxus chinensis. Biotechnology Letters 22, 1561–1564 (2000). https://doi.org/10.1023/A:1005684901329

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  • DOI: https://doi.org/10.1023/A:1005684901329

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