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Testing for Food Intolerance: New Markets in the Age of Biocapital

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Abstract

Testing for food allergy/intolerance is a rapidly expanding market. We present an exploration of the efforts of one of the market leading companies in this sector to promote and justify their product in the face of considerable opposition from conventional medicine, as well as a range of alliances with patient groups, so-called ‘lifestyle gurus’ and their customers. In extracting the latent value of an immunoglobin called IgG, testing companies engage with and extend entrepreneurial patienthood and new forms of pastoral expertise in their efforts to identify and manage a group of low-level chronic conditions that resonate with contemporary social unease about the hazards of modernity. Rather than foregrounding novelty and hope, we found that a great deal of emphasis was placed upon establishing conventionality with business practice and scientific method, and relief from the past. We also found that the local circuits and networks of engagement, in which the company operated to secure their reputation and extend their market, were vitally important. We end by reflecting upon the implications of our analysis for contemporary scholarship on biocapitalism.

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Notes

  1. 1 Immunoglobulins (antibodies) are proteins produced by plasma cells (or B-cells, a type of lymphocyte), which are designed to control the immune response in extracellular fluids by binding to substances in the body that are recognized as foreign antigens. Each Ig unit is made up of two heavy chains and two light chains and has two antigen-binding sites. Antibodies are diverse, with more than 1010 possible variations, yet each antibody is designed to recognize only a specific antigen. Initially bound to B-cells, upon encountering its specific antigen, an antibody/antigen complex stimulates the B-cell to produce copies of the antibody with the aid of helper T-cells. The new antibodies, which are all designed to recognize the infecting antigen, are released into the intercellular fluid where they bind to the infecting antigen, identifying it for destruction by phagocytes and the complement system. Immunoglobulins also play a central role in allergies, when they bind to antigens that are not necessarily a threat to health and provoke an inflammatory reaction. There are five main types of antibody: IgA; IgD; IgE; IgG; and IgM, of which IgA, IgG and IgM are the most common.

  2. 2 ESRC Award RES-000-23-1134.

  3. 3 See URL (accessed March 2009): www.gillianmckeith.info/yourbody/health/digestivedisorders/gillianmckeithfoodintolerances.php

  4. 4 See URL (accessed March 2009): www.patrickholford.com/content.asp?id_Content=1573; see also Holford and Braly (2005).

References

  • Allergy UK (2008). Food allergy and intolerance awareness week, 21–26 January, press release, URL (accessed April 2008): www.allergyuk.org/news_food_allergy_intolerance08.aspx

  • Asero R., Ballmer-Weber B.K., Beyer K., Conti A., Dubakiene R., Fernandez-Rivas M. et al. (2007). IgE-mediated food allergy diagnosis: Current status and new perspectives. Molecular Nutrition & Food Research, 51, 135–147.

    Google Scholar 

  • Bailey E. (1995). Bad reactions. Sunday Times, 29 October.

  • Barnes R.M.R. (1995). IgG and IgA antibodies to dietary antigens in food allergy and intolerance. Clinical and Experimental Allergy, 25(Suppl. 1), 7–9.

    Google Scholar 

  • Barrett S. (2002). Stay away from cytotoxic testing, URL (accessed April 2008): www.quackwatch.org/01QuackeryRelatedTopics/Tests/cyto.html

  • Barrett S. (2008). Allergies: Dubious diagnosis and treatment, URL (accessed April 2008): www.quackwatch.org/01QuackeryRelatedTopics/Tests/allergytests.html

  • BBC Radio 4 (2007). Allergic reactions, 22 May, URL (accessed June 2007): www.bbc.co.uk/radio4/science/allergicreactions.shtml

  • Black A. (1956). A new diagnostic method in allergic disease. Pediatrics, 17, 716–724.

    Google Scholar 

  • Braly J. (2001). Food allergy relief. Los Angeles, CA: Keats Publishing.

    Google Scholar 

  • Brostoff J., & Gamlin L. (1998). The complete guide to food allergy and intolerance, 3rd edn. London: Bloomsbury.

    Google Scholar 

  • Bryan W.T. & Bryan M.P. (1971). Cytotoxic reactions in the diagnosis of food allergy. Otolaryngol Clinics of North America, 4, 523–534.

    Google Scholar 

  • BSACI (2006). British Society for Allergy and Clinical Immunology, Annual Meeting, 10–12 July, Loughborough.

  • Buttriss J., & Schenker S. (2002). Introduction and Definitions. Adverse Reactions to Food: The Report of a British Nutrition Foundation Task Force. Oxford: Blackwell Science.

    Google Scholar 

  • Carling A. (2005). The truth about food allergy and food intolerance testing: Food fact sheet. British Dietetic Association, the BDA Food Allergy and Intolerance Specialist Group, September.

  • Chrysanthou M. (2002). Transparency and selfhood: Utopia and the informed body. Social Science & Medicine, 54, 469–479.

    Google Scholar 

  • Clover A. (2006). Are the dangers of childhood food allergy exaggerated? Yes. British Medical Journal, 333(September), 494–496.

    Google Scholar 

  • Crespo J.F., James J.M., & Rodriguez J. (2004). Diagnosis and therapy of food allergy. Molecular Nutrition & Food Research, 48, 347–355.

    Google Scholar 

  • Dixon H.S. (1997a). Food allergy signs and symptoms. In Trevino R. & Dixon H. (Eds), Food allergy, 36–60. New York: Thieme.

    Google Scholar 

  • Dixon H.S. (1997b). The diagnosis of food allergy. In Trevino R., & Dixon H., (Eds),Food allergy, 61–80. New York: Thieme.

    Google Scholar 

  • Dixon H.S. (2000). Treatment of delayed food allergy based on specific immunoglobulin G RAST testing. Otolaryngology—Head and Neck Surgery, 123, 48–54.

    Google Scholar 

  • Dockhorn R. (1987). Clinical studies of food allergy in infants and children. Annals of Allergy, 59(5 Pt 2), 137–140.

    Google Scholar 

  • FDA (Food and Drug Administration) (1985). Sec. 370.100 cytotoxic testing for allergic diseases (Compliance policy guide 7124.27), issued 19 March 1985, revised March 1995, URL (accessed March 2009): www.fda.gov/ora/compliance_ref/cpg/cpgdev/cpg370-100.html

  • FSA (Food Standards Agency) (2007) Food allergy and food intolerance, URL (accessed October 2008): www.food.gov.uk/multimedia/webpage/allergy/

  • Graham J. (2008). Facilitating regulation: The dance of statistical significance and clinical meaningfulness in standardizing technologies for dementia. BioSocieties, 3, 241–263.

    Google Scholar 

  • Holford P., & Braly J. (2005). Hidden food allergies: Is what you eat making you ill? London: Piatkus.

    Google Scholar 

  • Holgate S., & Ewan P. (Eds) (2003). Allergy: The unmet need. Report of the Royal College of Physicians Working Party on the Provision of Allergy Services in the UK. London: Royal College of Physicians.

  • Hope J. (2004). How allergy suffers are let down by the NHS. Daily Mail, 2 November, 31.

  • House of Lords (2007). Allergy. Science and Technology Committee, 6th Report of Session 2006–2007, vol. 1. London: The Stationery Office.

  • Jackson M. (2006). Allergy: The history of a modern malady. London: Reaktion Books.

    Google Scholar 

  • Jackson W.F. (2003). Food allergy. Washington, DC: ILSI Press.

    Google Scholar 

  • Janeway C., Travers P., Walport M., & Shlomchik M. (2001). Immunobiology: The immune system in health and disease, 5th edn. New York: Garland Publishing.

    Google Scholar 

  • Johansson S.G.O. (2003). Allergy: The discovery of immunoglobulin E to today. Clinical and Experimental Allergy Reviews, 3, 3–4.

    Google Scholar 

  • Johansson S.G.O., Hourihane J.O.B., Bousquet J., Bruijnzeel-Koomen C., Dreborg S., Haahtela T. et al. (2001). A revised nomenclature for allergy: An EAACI position statement from the EAACI nomenclature task force. Allergy, 56, 813–824.

    Google Scholar 

  • Johansson S.G.O., Bieber T., Dahl R., Friedmann P.S., Lanier B.Q., Lockey R.F. et al (2004). Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003. Journal of Allergy and Clinical Immunology, 113, 832–836.

    Google Scholar 

  • Kerr A. (2004). Genetics and society: A sociology of disease. London: Routledge.

    Google Scholar 

  • Kimber I., & Dearman R.J. (2002). Factors affecting the development of food allergy. Proceedings of the Nutrition Society, 61, 435–439.

    Google Scholar 

  • Latour B. (2005). Reassembling the social: An introduction to Actor-Network Theory. Oxford: Oxford UP.

    Google Scholar 

  • Lessof M. (1983). Food intolerance and allergy—A review. Quarterly Journal of Medicine, New Series 52(206), 111–119.

    Google Scholar 

  • Lessof M. (1985). Food intolerance. Proceedings of the Nutrition Society, 44, 121–125.

    Google Scholar 

  • Lessof M. (2002). Common food allergies. In Buttriss J. (Ed.), Adverse reactions to food: The report of the British Nutrition Foundation task force. Oxford: Blackwell Science.

    Google Scholar 

  • Mansfield S. (2006). So we're allergic to our diet? It's a complaint that's hard to swallow. The Scotsman, 23 January, 10.

  • Marber I. (2005). It must have been something I ate. Daily Telegraph, 1 August, 20.

  • Mills C. (2007). Minutes of evidence taken before the House of Lords, the Select Committee on Science and Technology (Sub-committee 1) Allergy, un-revised, proof copy, Ev. 11, 15 March.

  • Mitman G. (2007). Breathing space. New Haven, CT: Yale UP.

    Google Scholar 

  • Nettleton S., Woods B., Burrows R., & Kerr A. (forthcoming 2009). Experiencing food allergy and food intolerance: An analysis of lay accounts. Sociology.

  • Novas C., & Rose N. (2000). Genetic risk and the birth of the somatic individual. Economy and Society, 29, 485–513.

    Google Scholar 

  • Ortolani C., Ispano M., Scibilia J., & Pastorello E.A. (2001). Introducing chemists to food allergy. Allergy, 56(Suppl. 67), 5–8.

    Google Scholar 

  • Osterballe M., & Bindslev-Jensen C. (2003). Threshold levels in food challenge and specific IgE in patients with egg allergy: Is there a relationship? Journal of Allergy and Clinical Immunology, 112, 196–201.

    Google Scholar 

  • Parish W.E. (1970). Short-term anaphylactic IgG antibodies in human sera. Lancet, 2(7673), 591–592.

    Google Scholar 

  • Prentice T. (1985). Food allergy diets harmful. The Times, 9 July.

  • Rajan K.S. (2006). Biocapital: The constitution of postgenomic life. Durham, NC: Duke UP.

    Google Scholar 

  • Revill J. (2007). NHS swamped by an epidemic of allergies. The Observer, 10 June.

  • Roberts C., & Franklin S. (2006). Born and made: An ethnography of preimplantation genetic diagnosis. Berkeley: University of California Press.

    Google Scholar 

  • Rose N. (2006). The politics of life itself: Biomedicine, power and subjectivity in the twenty-first century. Princeton, NJ: Princeton UP.

    Google Scholar 

  • Sampson H.A. (2001). ‘Utility of food-specific IgE concentrations in predicting symptomatic food allergy. Journal of Allergy and Clinical Immunology, 107, 891–896.

    Google Scholar 

  • Sampson H.A. (2004). Update on food allergy. Journal of Allergy and Clinical Immunology, 113, 805–819.

    Google Scholar 

  • Sampson H.A., & Burks W.A. (1996). Mechanisms of food allergy. Annual Review of Nutrition, 16, 161–177.

    Google Scholar 

  • Sampson H.A., & Ho D.G. (1997). Relationship between food-specific IgE concentrations and the risk of positive food challenges in children and adolescents. Journal of Allergy and Clinical Immunology, 100, 444–451.

    Google Scholar 

  • Scadding G. (2007). Minutes of evidence taken before the House of Lords: The Select Committee on Science and Technology (Sub-committee 1) Allergy, un-revised, proof copy, Ev. 11, 15 March.

  • Senna G., Bonadonna P., Schiappoli M., Leo G., Lombardi C., & Passalacqua G. (2005). Pattern of use and diagnostic value of complementary/alternative tests for adverse reactions to food. Allergy, 60, 1216–1217.

    Google Scholar 

  • Sense about Science (2008). Making sense of testing. London: Sense about Science in collaboration with the Royal College of Pathologists, the Association for Clinical Biochemistry and the Foundation for Genomics & Population Health.

  • Shaffer R., Kuczynski K., & Skinner D. (2008). Producing genetic knowledge and citizenship through the Internet: Mothers, pediatric genetics, and cybermedicine. Sociology of Health & Illness, 30, 145–159.

    Google Scholar 

  • Shakib F., McLaughan P., & Stanworth D.R. (1977). Elevated serum IgE and IgG4 in patients with atopic dermatitis. British Journal of Dermatology, 97, 59–63.

    Google Scholar 

  • Sicherer S.H. (2002). Review: Food allergy. Lancet, 360(31 August), 701–710.

    Google Scholar 

  • Sporik R., Hill D.J., & Hosking C.S. (2000). Specificity of allergen skin testing in predicting positive open food challenges to milk, egg and peanut in children. Clinical and Experimental Allergy, 30(11), 1540–1546.

    Google Scholar 

  • Strobel S. (2002). Clinically validated diagnostic tests and non-validated procedures of unproven value. In Buttriss J. (Ed.), Adverse reactions to food: The report of the British Nutrition Foundation task force. Oxford: Blackwell Science.

    Google Scholar 

  • Thacker E. (2005). The global genome: Biotechnology, politics, and culture. Cambridge, MA: MIT Press.

    Google Scholar 

  • Thompson R.C. (1984). The flaw in cytotoxic testing: There's no proof it works—testing blood for allergies. FDA Consumer, October, URL (accessed March 2009): findarticles.com/p/articles/mi_m1370/is_v18/ai_3456415

  • Walby C., & Mitchell T. (2006). Tissue economies: Blood, organs and cell lines in late capitalism. Durham, NC: Duke UP.

    Google Scholar 

  • Wahlberg A. (2008). Pathways to plausibility: When herbs become pills. BioSocieties, 3, 37–56.

    Google Scholar 

  • Willey Jo, & Sadler R. (2006). Misery ends for allergy suffers. The Express, 9 September, 1.

  • Woods R.K., Stoney R.M., Raven J., Walters E.H., Abramson M., & Thien F.C. (2002). Reported adverse food reactions overestimate true food allergy in the community. European Journal of Clinical Nutrition, 56, 31–36.

    Google Scholar 

  • Woolgar S. (2002). Five rules of virtuality. In Woolgar S. (Ed.), Virtual society? Technology, cyberbole, reality, 1–22. Oxford: Oxford UP.

    Google Scholar 

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Kerr, A., Woods, B., Nettleton, S. et al. Testing for Food Intolerance: New Markets in the Age of Biocapital. BioSocieties 4, 3–24 (2009). https://doi.org/10.1017/S1745855209006401

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