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Clinical and prognostic aspects of gastric carcinoma in the elderly

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Journal of Gastrointestinal Surgery Aims and scope

Abstract

The aim of the present study was to analyze the influence of various factors on the prognosis for elderly patients with gastric carcinoma. Forty-eight patients aged =>65 years admitted to Padova General Hos-pital were divided into two groups by age (<75 or >75 years). They all had a histologically confirmed diagnosis of gastric adenocarcinoma. Information on their clinicopathological characteristics was col-lected from the Padova Hospital medical records. On univariate analysis, significant prognostic factors in the two age groups were gender, stage, histotype (Lauren’s intestinal type), Charlson index, and type of surgery (curative resection, palliative resection, and no surgery). On multivariate analysis, inde-pendent prognostic factors were the Charlson index, tumor stage, and age group. The 52-month survival rate was 72.7% for females and 12.5% for males for patients =>75 years (P = 0.01), while for the whole series of patients it was 67.5% for females and 29.9% for males (P = 0.003). The 17-month survival rate was 55.6% for surgically treated patients and 0% for the untreated cases in stage 4 (P = 0.03). Gastric cancer should be treated with conventional surgery even in the very elderly, since the survival rate for this age group does not differ significantly from the figures for younger patients.

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Authors and Affiliations

  1. Department of Medical and Surgical Sciences, Geriatrics Section, University of Padua, Padua, Italy

    Giulia Gasparini M.D.,  Emine Meral Inelmen M.D., Giuliano Enzi M.D., Cristina Santoro M.D. & Giuseppe Sergi M.D.

  2. Department of Surgical and Gastroenterologic Sciences, Division of Geriatric Surgery, University of Padua, Padua, Italy

    Fabrizio Cardin M.D. & Oreste Terranova M.D.

Authors
  1. Giulia Gasparini M.D.
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  2. Emine Meral Inelmen M.D.
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  3. Giuliano Enzi M.D.
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  4. Cristina Santoro M.D.
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  5. Giuseppe Sergi M.D.
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  6. Fabrizio Cardin M.D.
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  7. Oreste Terranova M.D.
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Correspondence to Emine Meral Inelmen M.D..

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Gasparini, G., Inelmen, E.M., Enzi, G. et al. Clinical and prognostic aspects of gastric carcinoma in the elderly. J Gastrointest Surg 10, 395–401 (2006). https://doi.org/10.1016/j.gassur.2005.07.002

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  • DOI: https://doi.org/10.1016/j.gassur.2005.07.002

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