Abstract
The aim of this study was to determine prognostic factors and outcome after liver resection for colorectal metastases in 102 patients over a period of 10 years. A stepwise procedure using proportional hazard regression analysis was used to identify prognostic factors. Estimated survival at 2 years was 71%, and at 5 years, 29% (Kaplan-Meier). Of 19 patients with isolated liver recurrence, 6 had a second metastasectomy; 4 of the 6 are still alive.Wefound that the number of hepatic lesions on computed tomography (P = 0.012), the interval between resection of the primary colon tumor and the hepatic metastasectomy (P = 0.012), and synchronicity of the primary and the hepatic metastasis (P = 0.048) showed evidence of independent prognostic value regarding survival. Resection of hepatic colorectal metastases may result in long-term survival. Patients with recurrence after a first liver resection may benefit from a repeat metastasectomy. Our data suggest there is no strong predictor of survival. Survival seems to decrease with increasing number of metastases found on computed tomography.
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Mutsaerts, E.L.A.R., van Ruth, S., Zoetmulder, F.A.N. et al. Prognostic factors and evaluation of surgical management of hepatic metastases from colorectal origin: A 10-year single-institute experience. J Gastrointest Surg 9, 178–186 (2005). https://doi.org/10.1016/j.gassur.2004.06.005
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DOI: https://doi.org/10.1016/j.gassur.2004.06.005