Abstract
In hybrid cultivated form, Dendranthema grandiflorum (Ramat.) Kitam., Asteraceae, flowers (Chrysanthemum morifolium Ramat.) were utilized in the production of extracts, which were analyzed for larvicidal activity against Aedes aegypti third instar larvae. Methanol and dichloromethane extracts showed LC50 values of 5.02 and 5.93 ppm, respectively. Using GC-MS, phytochemical analyses of the dichloromethane extract showed the presence of triterpenoids and fatty acids, while flavonoids and caffeoylquinic acids were shown to occur in the methanol extract by ESI Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (ESI-FT-ICR-MS). Triterpenoids and fatty acids are well known insecticidal compounds. From this study, it can be concluded that D. grandiflorum grown for floriculture, as an agribusiness, can have additional applications as raw material for the production of insecticidal products.
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Acknowledgments
The authors thank CAPES and CNPq for financial support and Prof. Sandra Zorat Cordeiro, UNIRIO-RJ, for the plant specimen deposit at the herbarium (Prof. Jorge Pedro Pereira Carauta).
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KCVWS (PhD student) collected and identified plant samples, ran the laboratory work, analyzed data, and drafted the paper. NKS,CES and GRB carried out biological studies. WR and GV performed mass spectrometry analysis and SRCS to chromatographic analysis. FGS performed a critical reading of the manuscript. AGS conducted statistical analysis. RMK designed the study, supervised the laboratory work and offered critical comments on the manuscript. All authors have read the final manuscript and approved the submission.
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Spindola, K.C.V.W., Simas, N.K., dos Santos, C.E. et al. Dendranthema grandiflorum, a hybrid ornamental plant, is a source of larvicidal compounds against Aedes aegypti larvae. Rev. Bras. Farmacogn. 26, 342–346 (2016). https://doi.org/10.1016/j.bjp.2016.01.003
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DOI: https://doi.org/10.1016/j.bjp.2016.01.003