Summary
111In-antimyosin scintigraphy offers a valuable noninvasive method for early detection of clinically silent cardiac involvement in patients with systemic sclerosis, even in the absence of left ventricular dysfunction. In these patients with positive antimyosin study results, intense pharmacologic treatment with vasodilators may be warranted.
Similar content being viewed by others
References
Bulkley BH, Ridolfi RL, Salyer WR, Hutchins GM. Myocardial lesions of progressive systemic sclerosis: a cause of cardiac dysfunction. Circulation 1976;53:483–90.
Lekakis J, Mavrikakis M, Emmanuel M, Prassopoulos V, Papazoglou S, Papamichael C, et al. Cold-induced coronary Raynaud's phenomenon in patients with systemic sclerosis. Clin Exp Rheumatol 1998;16:135–40.
Khaw BA, Narula J. Antibody imaging in the evaluation of cardiovascular diseases. J Nucl Cardiol 1994;1:457–76.
Sarda L, Georges C, Assayag P, Lebtahi R, Faraggi M, Palazzo E, et al. Utility of indium-111-antimyosin scintigraphy for diagnosis of myocardial damage in systemic sclerosis. J Nucl Med 1997;38:1759–61.
Duboc D, Kahan A, Maziere B, Loch C, Crouzel C, Menkes CJ, et al. The effect of nifedipine on myocardial perfusion and metabolism in systemic sclerosis. A positron emission tomographic study. Arthritis Rheum 1991;34:198–203.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Lekakis, J., Mavrikakis, M., Prassopoulos, V. et al. Scleroderma heart disease: An unusual cause of positive antimyosin cardiac imaging. J Nucl Cardiol 6, 91–92 (1999). https://doi.org/10.1016/S1071-3581(99)90069-7
Issue Date:
DOI: https://doi.org/10.1016/S1071-3581(99)90069-7