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The use of natural extracts with photoprotective activity: a 2015–2023 patent prospection

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Abstract

Synthetic sunscreen offers protection against excessive exposure to ultraviolet (UV) radiation from the sun, and protects the skin from possible damage. However, they have low efficacy against the formation of reactive oxygen species (ROS), which are highly reactive molecules that can be generated in the skin when it is exposed to UV radiation, and are known to play a role in oxidative stress, which can contribute to skin aging and damage. Thus, there is an ongoing search for sunscreens that do not have these negative effects. One promising source for these is natural products. Therefore, the current patent review summarizes topical formulations made from natural compounds that have antioxidant properties and can be used as photoprotective or anti-aging agents, either using a single natural extract or a combination of extracts. The review reports basic patent information (applicant country, type of applicant, and year of filing) and gives details about the invention, including its chemical composition, and the in vitro and in vivo tests performed. These patents describe natural products that can be used to protect the skin and validate their efficacy, and safety, in addition to standardizing their formulations. The compositions described illustrate the consistent innovation in the use of natural products to protect against UV damage and photoaging disorders, a promising field which is receiving growing global recognition.

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Funding

This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brasil (CAPES)—Finance Code 001. The authors would like to thank CAPES, FAPITEC/SE and CNPq (Brazil) for their financial support.

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Authors and Affiliations

  1. Postgraduate Program in Pharmaceutical Sciences, Department of Pharmacy, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil

    Ana Maria Santos Oliveira & Mairim Russo Serafini

  2. Postgraduate Program in Pharmaceutical Sciences, Department of Life Sciences, State University of Bahia, Salvador, Bahia, Brazil

    Daniel de Souza Batista, Tailaine Nascimento de Castro, Izabel Almeida Alves, Milleno Dantas Mota & Edith Cristina Laignier Cazedey

  3. Department of Medicines, Faculty of Pharmacy, Federal University of Bahia, Salvador, Bahia, Brazil

    Izabel Almeida Alves, Ricardo Bizogne Souto & Edith Cristina Laignier Cazedey

  4. Department of Botany, Sri Sarada College for Women (Autonomous), Periyar University, Salem, India

    Gomathi Rajkumar

Authors
  1. Ana Maria Santos Oliveira
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  2. Daniel de Souza Batista
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  3. Tailaine Nascimento de Castro
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  4. Izabel Almeida Alves
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  5. Ricardo Bizogne Souto
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  6. Milleno Dantas Mota
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  7. Mairim Russo Serafini
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  8. Gomathi Rajkumar
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  9. Edith Cristina Laignier Cazedey
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Contributions

Ana Maria Santos Oliveira: conceptualization, formal analysis, investigation, methodology, writing—original draft, writing—review and editing, visualization. Daniel de Souza Batista: writing—original draft, writing—review and editing, visualization. Tailaine Nascimento de Castro: writing—original draft, writing—review and editing, visualization. Izabel Almeida Alves: writing—original draft, writing—review and editing, visualization. Ricardo Bizogne Souto: writing—original draft, writing—review and editing, visualization. Milleno Dantas Mota: methodology, writing—original draft. Mairim R. Serafini: conceptualization, methodology, visualization, supervision. Edith Cristina Laignier Cazedey: conceptualization, methodology, writing—review and editing, funding acquisition, supervision.

Corresponding author

Correspondence to Ana Maria Santos Oliveira.

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Oliveira, A.M.S., de Souza Batista, D., de Castro, T.N. et al. The use of natural extracts with photoprotective activity: a 2015–2023 patent prospection. Photochem Photobiol Sci (2024). https://doi.org/10.1007/s43630-024-00559-w

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