Abstract
Triple-negative breast cancer stands out as the most formidable subtype of breast cancer. Currently, there is a lack of specialized treatments for this particularly invasive form of cancer. A characteristic feature of this cancer is the overexpression of proangiogenic proteins, making the regulation of tumor angiogenesis a promising therapeutic approach. This article offers a comprehensive review of phytochemical studies from 2013 to 2023 that demonstrate anti-angiogenic properties. By integrating the latest evidence concerning these compounds, the review sets the stage for future research directions, aiming to harness the power of phytochemical compounds against triple-negative breast cancer.
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Reproduced from the Open Access article by Jin et al. (2019)
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Acknowledgements
The author expresses sincere appreciation to Prof. Rogelio Pereda-Miranda, the Editor-in Chief of the Revista Brasileira de Farmacognosia, for his invaluable guidance that enhanced the quality of this review.
Funding
This project is funded under the Fundamental Research Grant Scheme (FRGS) for 2023 (FRGS/1/2023/STG04/UNIKL/02/2).
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Poh-Yen, K. Phytochemical Small Molecules as Potential Anti-angiogenesis Targeted Therapy for Triple-Negative Breast Cancer. Rev. Bras. Farmacogn. 34, 451–466 (2024). https://doi.org/10.1007/s43450-023-00491-7
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DOI: https://doi.org/10.1007/s43450-023-00491-7