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Insecticidal bioactive compounds derived from Cladosporium cladosporioides (Fresen.) G.A. de Vries and Acremonium zeylanicum (Petch) W. Gams & H.C. Evans

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Abstract

Entomopathogenic fungi (EPF) are the main microbiological control agents of insect pests. One of the key factors in the pathogenicity of EPF is the production of insecticidal bioactive compounds. Therefore, the metabolites of two isolates of EPF, Cladosporium cladosporioides (Fresen.) G.A. de Vries (AF98) and Acremonium zeylanicum (Petch) W. Gams & H.C. Evans (IR87), were analyzed. The presence of insecticidal toxic cyclic peptides such as Bassianolide in C. cladosporioides AF98 metabolites was detected by HPLC. Moreover, GC–MS analysis showed some toxic compounds, including 3,4-Dihydro-7,12-Dihydroxy-7,12-Imethylbenz[A]Anthracene, 1,2,3,4-Tetrahydro-1,1,4,4,6-Pentamethyl-5,7-Dinitronaphthalene, and 1,2,3,4-Tetrahydro-1,1,4,4,6-Pentamethyl-5,7-Dinitronaphthalene in the metabolites purified from A. zeylanicum IR87. Also, a few hazardous compounds, including 3,5-di-tert-butyl-4-trimethylsiloxytoluene, bis(2-Ethylhexyl) phthalate, di-n-octyl phthalate, 1-pentadecene, and 1-eicosene were found which might be toxic against insects. This is the first report on the detection of toxic peptides from C. cladosporioides. These results showed that multiple compounds are likely contributed to the insecticidal effects of the EPF.

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Data availability

The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Acknowledgements

We thank staffs of Citrus and Subtropical Fruits Research Center of Iran for their technical supports.

Funding

The research was financially supported by Agricultural Sciences and Natural Resources University of Khuzestan (Grant No. 9428412).

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Authors and Affiliations

  1. Department of Plant Protection, Faculty of Agriculture, Agricultural Sciences and Natural Resources University of Khuzestan, Mollasani, Ahvaz, 6341773637, Iran

    Khaled Mousavi, Ali Rajabpour, Mohamad Hamed Ghodoum Parizipour & Fatemeh Yarahmadi

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  1. Khaled Mousavi
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  2. Ali Rajabpour
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  3. Mohamad Hamed Ghodoum Parizipour
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  4. Fatemeh Yarahmadi
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AR, MHGP and FY designed the experiments. KM performed the experiments. AR wrote the manuscript. The manuscript studied and certificated by all authors.

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Correspondence to Ali Rajabpour.

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Mousavi, K., Rajabpour, A., Parizipour, M.H.G. et al. Insecticidal bioactive compounds derived from Cladosporium cladosporioides (Fresen.) G.A. de Vries and Acremonium zeylanicum (Petch) W. Gams & H.C. Evans. J Plant Dis Prot 130, 543–549 (2023). https://doi.org/10.1007/s41348-022-00701-9

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