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Parameter Study on How the Cervical Disc Degeneration Affects the Segmental Instantaneous Centre of Rotation

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Abstract

Purpose

Methods

Four degenerated models (anterior osteophyte enlargement, intervertebral disc height loss, endplates curvature flattening, and degeneration of the disc material properties) were established by appropriately modifying the geometry or material properties of a single segment (C5/6) using the finite element approach (FEA). A 73.6 N follower load and a pure moment load of 1 N-m simulated to physiological motion were applied to all FEA models and motion paths of the ICR were compared.

Results

The variable “intervertebral disc height loss” had the most pronounced effect on the motion path of the ICR of the degenerated segment, and the mean ICR locations of the degenerative models with different degrees of “intervertebral disc height loss” moved markedly forward at the degenerated segment.

Conclusion

Abnormal ICR motion patterns should be noted during prostheses design and surgical strategy development in the clinic and that abnormally located ICR motion paths need restoring to normal physiological positions. The results of this paper may provide valuable reference for the future design of prostheses that mimic the morphology of the human intervertebral disc based on the ICR locations.

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Data Availability

The datasets used and/or analysed during the current study are available

from the corresponding author on reasonable request.

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Funding

This work has been supported by the National Natural Science Foundation of China (NSFC Nos. 11602172, 12072233), National Natural Science Foundation of Tianjin (No. 21JCYBJC01210), and Key Laboratory of spine and spinal cord injury repair and regeneration (Tongji University), Ministry of Education.

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Authors and Affiliations

  1. Tianjin Key Laboratory for Advanced Mechatronic System Design and Intelligent Control, School of mechanical engineering, Tianjin University of Technology, Tianjin, 300384, China

    Hong Zhang, Bin Zhang, Ya-Nan Ren, Xin Wang, Jing-Jing Feng & Cheng-Fei Du

  2. National Demonstration Center for Experimental Mechanical and Electrical Engineering Education, Tianjin, 300384, China

    Hong Zhang, Bin Zhang, Ya-Nan Ren, Xin Wang, Jing-Jing Feng & Cheng-Fei Du

  3. Department of Orthopaedic Surgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, China

    Dacheng Sang & Baoge Liu

  4. Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of Ministry of Education, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, China

    Rui Zhu

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Contributions

HZ, BZ, Y-NR, XW, J-JF, C-FD, and RZ carried out the model development and simulation and data analysis and drafted the manuscript. HZ, C-FD, and RZ participated in the study design. HZ, C-FD, XW, and RZ participated in revising the manuscript. All authors read and approved the final manuscript.

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Correspondence to Cheng-Fei Du, Baoge Liu or Rui Zhu.

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Zhang, H., Sang, D., Zhang, B. et al. Parameter Study on How the Cervical Disc Degeneration Affects the Segmental Instantaneous Centre of Rotation. J. Med. Biol. Eng. 43, 163–175 (2023). https://doi.org/10.1007/s40846-023-00779-y

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