Development of the ArthritisPower Registry, the platform that was used to conduct this study, was partially supported through a Patient-Centered Outcomes Research Institute (PCORI) award (PPRN-1306-04811) and by NIAMS P30AR072583. The study was also partially funded by Amgen Inc. Amgen funded the journal’s Rapid Service and Open Access Fees. All statements in this article, including its findings and conclusions, are solely those of the authors and do not necessarily represent the views of PCORI, or its Board of Governors or Methodology Committee.
All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this article, take responsibility for the integrity of the work as a whole, and have given their approval for this version to be published.
Elaine Karis, Gregory Kricorian, Jeffrey R. Curtis, Lang Chen, Laura Stradford, Shilpa Venkatachalam, and William Benjamin Nowell were involved in study conception and design; Hong Zhao, Jeffrey R. Curtis, Kelly Gavigan, and William Benjamin Nowell were involved in acquisition of data; Elaine Karis, Fenglong Xie, Gregory Kricorian, Huifeng Yun, Hong Zhao, Jeffrey R. Curtis, Kelly Gavigan, Lang Chen, Scott Stryker, Shilpa Venkatachalam, and William Benjamin Nowell were involved in analysis and interpretation of data. All authors were involved in revising the article critically for important intellectual content and approved the final version to be submitted for publication.
Medical Writing and Editorial Assistance
Medical writing support was funded by Amgen Inc. and provided by Kathryn Boorer, PhD, of KB Scientific Communications, LLC, and Kripa Madnani, PhD, of Cactus Life Sciences (part of Cactus Communications).
William Benjamin Nowell, Kelly Gavigan, Laura Stradford, and Shilpa Venkatachalam are employees of Global Healthy Living Foundation (GHLF); GHLF has received research funding support from AbbVie, Amgen, Bristol-Myers Squibb, Eli Lilly and Company, Janssen, PCORI, Pfizer, Sanofi Genzyme, and UCB. Elaine Karis, Scott Stryker, and Gregory Kricorian are employees of and own stock in Amgen Inc. Huifeng Yun has received research support from Pfizer. Jeffrey R. Curtis has received grant support, research support, and consulting fees from AbbVie, Amgen, BMS, Corrona, Eli Lilly, Janssen, Myriad, Pfizer, Regeneron, Roche, and UCB. Fenglong Xie, Hong Zhao, and Lang Chen have nothing to disclose.
Compliance with Ethics Guidelines
The study was conducted in accordance with ethical principles of the Declaration of Helsinki 1964, and its later amendments. The study protocol was approved by Advarra Institutional Review Board (Advarra IRB Protocol #00033156). The current study was an ancillary study of the registry during which eligible ArthritisPower members opted in for additional data collection. Because this was a sub-study that did not go beyond collection and analysis of patient-reported outcome or other observational data being routinely collected by the Registry, no additional consent or addendum to consent was required.
The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request. Qualified researchers may request data from Amgen clinical studies. Complete details are available at the following: https://wwwext.amgen.com/science/clinical-trials/clinical-data-transparency-practices/clinical-trial-data-sharing-request/Journals.
The authors thank the study participants for their time and willingness to participate. The authors also wish to thank David Curtis for his contribution to the participant workflow design.